A strategy for co-translational folding studies of ribosome-bound nascent chain complexes using NMR spectroscopy

被引:0
|
作者
Anaïs M E Cassaignau
Hélène M M Launay
Maria-Evangelia Karyadi
Xiaolin Wang
Christopher A Waudby
Annika Deckert
Amy L Robertson
John Christodoulou
Lisa D Cabrita
机构
[1] Institute of Structu,
[2] ral and Molecular Biology,undefined
[3] University College London and Birkbeck College,undefined
[4] University of London,undefined
来源
Nature Protocols | 2016年 / 11卷
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摘要
Cassaignau et al. provide a strategy for large-scale production and analysis of translationally arrested, isotopically labelled ribosome-bound nascent chains, enabling high-resolution co-translational protein folding studies using NMR spectroscopy.
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页码:1492 / 1507
页数:15
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