TransPrEP: Results from the Pilot Study of a Social Network-Based Intervention to Support PrEP Adherence Among Transgender Women in Lima, Peru

被引：0

作者：

Jesse Clark

Sari Reisner

Amaya Perez-Brumer

Leyla Huerta

Hugo Sanchez

Kathleen Moriarty

Maria Mamani Luque

Hideaki Okochi

Ximena Salazar

Matthew Mimiaga

Jorge Sanchez

Monica Gandhi

Kenneth H. Mayer

Javier R. Lama

机构：

[1] UCLA Geffen School of Medicine,Dalla Lana School of Public Health

[2] The Fenway Institute,Centro de Investigaciones Tecnológicas Biomédicas y Medioambientales

[3] Boston Children’s Hospital,undefined

[4] University of Toronto,undefined

[5] Feminas,undefined

[6] Epicentro,undefined

[7] Asociacion Civil Impacta Salud y Educacion,undefined

[8] University of California,undefined

[9] Instituto de Estudios de Salud Sexual y Derechos Humanos,undefined

[10] Brown University School of Public Health,undefined

[11] Universidad Nacional San Marcos,undefined

[12] Beth Israel Deaconess Medical Center,undefined

[13] Harvard Medical School,undefined

来源：

AIDS and Behavior | 2021年 / 25卷

关键词：

Pre-exposure prophylaxis (PrEP); Transgender women; Adherence; Latin america;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

We conducted a pilot randomized controlled trial of a social network-based intervention to promote PrEP adherence among transgender women (TW) in Lima, Peru. We enrolled 89 TW from six social networks and cluster-randomized them 1:1 to standard of care (n = 44) or the TransPrEP intervention (n = 45). Core workshops discussed strategies to support PrEP adherence and defined group adherence objectives. Maintenance workshops discussed participants’ experiences taking PrEP and collective adherence goals. At 3-month follow-up, we evaluated 40 participants and obtained 29 hair samples for tenofovir level measurements. Though no significant differences were observed, 36.4% (4/11) of participants of TransPrEP participants and 10.0% (1/10) of control participants had tenofovir levels > 0.023 ng/mg, consistent with ≥ 4 doses per week. 81.8% (9/11) of intervention and 40.0% (4/10) of control participants had any detectable tenofovir in their hair. Pilot assessment of our network-based intervention suggested a trend towards improved PrEP adherence, measured objectively, for TW in Peru.

引用

页码：1873 / 1883

页数：10

共 185 条

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