NO/cGMP/pCREB re-activation reverses cognition deficits and attenuates amyloid-β neuropathology in transgenic models of Alzheimer’s disease

被引:0
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作者
Gregory RJ Thatcher
Jia Luo
Lawren VandeVrede
Zhihui Qin
Sue Lee
Ramy Abdelhamid
Brian M Bennett
Mary Jo LaDu
Leon Tai
John Larson
机构
[1] University of Illinois College of Pharmacy,Department of Medicinal Chemistry & Pharmacognosy
[2] University of Illinois at Chicago (UIC),Department of Biomedical and Molecular Sciences
[3] UICentre (drug discovery @ UIC),Department of Anatomy and Cell Biology
[4] UIC,Department of Psychiatry
[5] cGC Pharma Inc.,undefined
[6] Chicago,undefined
[7] IL,undefined
[8] Faculty of Health Sciences,undefined
[9] UIC,undefined
[10] Neuropsychiatric Institute,undefined
[11] UIC,undefined
关键词
Transgenic Mouse Model; Gene Expression Program; Guanylyl Cyclase; Soluble Guanylyl Cyclase; Human ApoE4;
D O I
10.1186/2050-6511-14-S1-P72
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