NO/cGMP/pCREB re-activation reverses cognition deficits and attenuates amyloid-β neuropathology in transgenic models of Alzheimer’s disease

被引:0
|
作者
Gregory RJ Thatcher
Jia Luo
Lawren VandeVrede
Zhihui Qin
Sue Lee
Ramy Abdelhamid
Brian M Bennett
Mary Jo LaDu
Leon Tai
John Larson
机构
[1] University of Illinois College of Pharmacy,Department of Medicinal Chemistry & Pharmacognosy
[2] University of Illinois at Chicago (UIC),Department of Biomedical and Molecular Sciences
[3] UICentre (drug discovery @ UIC),Department of Anatomy and Cell Biology
[4] UIC,Department of Psychiatry
[5] cGC Pharma Inc.,undefined
[6] Chicago,undefined
[7] IL,undefined
[8] Faculty of Health Sciences,undefined
[9] UIC,undefined
[10] Neuropsychiatric Institute,undefined
[11] UIC,undefined
关键词
Transgenic Mouse Model; Gene Expression Program; Guanylyl Cyclase; Soluble Guanylyl Cyclase; Human ApoE4;
D O I
10.1186/2050-6511-14-S1-P72
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Dihydromyricetin Ameliorates Behavioral Deficits and Reverses Neuropathology of Transgenic Mouse Models of Alzheimer's Disease
    Liang, Jing
    Lindemeyer, A. Kerstin
    Shen, Yi
    Lopez-Valdes, Hector E.
    Martinez-Coria, Hilda
    Shao, Xuesi M.
    Olsen, Richard W.
    NEUROCHEMICAL RESEARCH, 2014, 39 (06) : 1171 - 1181
  • [2] Dihydromyricetin Ameliorates Behavioral Deficits and Reverses Neuropathology of Transgenic Mouse Models of Alzheimer’s Disease
    Jing Liang
    A. Kerstin Lindemeyer
    Yi Shen
    Héctor E. López-Valdés
    Hilda Martínez-Coria
    Xuesi M. Shao
    Richard W. Olsen
    Neurochemical Research, 2014, 39 : 1171 - 1181
  • [3] Erratum to: Dihydromyricetin Ameliorates Behavioral Deficits and Reverses Neuropathology of Transgenic Mouse Models of Alzheimer’s Disease
    Jing Liang
    Héctor E. López-Valdés
    Hilda Martínez-Coria
    A. Kerstin Lindemeyer
    Yi Shen
    Xuesi M. Shao
    Richard W. Olsen
    Neurochemical Research, 2014, 39 : 1403 - 1403
  • [4] Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
    Evandro F. Fang
    Yujun Hou
    Konstantinos Palikaras
    Bryan A. Adriaanse
    Jesse S. Kerr
    Beimeng Yang
    Sofie Lautrup
    Md Mahdi Hasan-Olive
    Domenica Caponio
    Xiuli Dan
    Paula Rocktäschel
    Deborah L. Croteau
    Mansour Akbari
    Nigel H. Greig
    Tormod Fladby
    Hilde Nilsen
    M. Zameel Cader
    Mark P. Mattson
    Nektarios Tavernarakis
    Vilhelm A. Bohr
    Nature Neuroscience, 2019, 22 : 401 - 412
  • [5] Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
    Fang, Evandro F.
    Hou, Yujun
    Palikaras, Konstantinos
    Adriaanse, Bryan A.
    Kerr, Jesse S.
    Yang, Beimeng
    Lautrup, Sofie
    Hasan-Olive, Md Mahdi
    Caponio, Domenica
    Dan, Xiuli
    Rocktaschel, Paula
    Croteau, Deborah L.
    Akbari, Mansour
    Greig, Nigel H.
    Fladby, Tormod
    Nilsen, Hilde
    Cader, M. Zameel
    Mattson, Mark P.
    Tavernarakis, Nektarios
    Bohr, Vilhelm A.
    NATURE NEUROSCIENCE, 2019, 22 (03) : 401 - +
  • [6] Valproic Acid Alleviates Memory Deficits and Attenuates Amyloid-β Deposition in Transgenic Mouse Model of Alzheimer's Disease
    Xuan, Ai-Guo
    Pan, Xue-Bing
    Wei, Peng
    Ji, Wei-Dong
    Zhang, Wen-Juan
    Liu, Ji-Hong
    Hong, Le-Peng
    Chen, Wen-Liang
    Long, Da-Hong
    MOLECULAR NEUROBIOLOGY, 2015, 51 (01) : 300 - 312
  • [7] Valproic Acid Alleviates Memory Deficits and Attenuates Amyloid-β Deposition in Transgenic Mouse Model of Alzheimer’s Disease
    Ai-Guo Xuan
    Xue-Bing Pan
    Peng Wei
    Wei-Dong Ji
    Wen-Juan Zhang
    Ji-Hong Liu
    Le-Peng Hong
    Wen-Liang Chen
    Da-Hong Long
    Molecular Neurobiology, 2015, 51 : 300 - 312
  • [8] The Combination of β-Asarone and Icariin Inhibits Amyloid-β and Reverses Cognitive Deficits by Promoting Mitophagy in Models of Alzheimer's Disease
    Wang, Nanbu
    Wang, Haoyu
    Pan, Qi
    Kang, Jian
    Liang, Ziwen
    Zhang, Ronghua
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, 2021
  • [9] Hippocampal Deficits in Amyloid-β-Related Rodent Models of Alzheimer's Disease
    Vyas, Yukti
    Montgomery, Johanna M.
    Cheyne, Juliette E.
    FRONTIERS IN NEUROSCIENCE, 2020, 14
  • [10] Aminostyrylbenzofuran Directly Reduces Oligomeric Amyloid-β and Reverses Cognitive Deficits in Alzheimer Transgenic Mice
    Lee, Sang-Hyun
    Kim, YoungSoo
    Kim, Hye Yun
    Kim, Young Hoon
    Kim, Maeng Sup
    Kong, Jae Yang
    Lee, Mun-Han
    Kim, Dong Jin
    Ahn, Young Gil
    PLOS ONE, 2014, 9 (04):