Clinical impact of the callosal angle in the diagnosis of idiopathic normal pressure hydrocephalus

被引：0

作者：

Kazunari Ishii

Tomonori Kanda

Aya Harada

Naokazu Miyamoto

Tetsuro Kawaguchi

Kenichi Shimada

Shingo Ohkawa

Takafumi Uemura

Toshiki Yoshikawa

Etsuro Mori

机构：

[1] Hyogo Brain and Heart Center,Department of Radiology and Nuclear Medicine

[2] Hyogo Brain and Heart Center,Department of Neurosurgery

[3] Hyogo Brain and Heart Center,Institute for Aging Brain and Cognitive Disorders

[4] Tohoku University Graduate School of Medicine,Department of Behavioral Neurology and Cognitive Neuroscience

来源：

European Radiology | 2008年 / 18卷

关键词：

Callosal angle; Idiopathic normal pressure hydrocephalus (INPH); Magnetic resonance imaging (MRI); Alzheimer’s disease;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The utility of measuring the corpus callosal angle (CA) for the diagnosis of idiopathic normal pressure hydrocephalus (INPH) was investigated. Three-dimensional magnetic resonance imaging (MRI) was performed in 34 INPH patients, 34 Alzheimer’s disease (AD) patients, and 34 normal control (NC) subjects. Measurement of the CA on the coronal MR images of the posterior commissure perpendicular to the anteroposterior commissure plane was performed for all subjects. The CA of the INPH group (mean ± SD, 66 ± 14°) was significantly smaller than those of the AD (104 ± 15°) and NC (112 ± 11°) groups. When using the threshold of the mean − 2SD value of the NC group (= 90°), an accuracy of 93%, sensitivity of 97%, and specificity of 88% were observed for discrimination of INPH from AD patients. Measuring the CA helps in differentiating INPH patients from AD and normally aged subjects.

引用

共 92 条

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