Investigating interactions between phentermine, dexfenfluramine, and 5-HT2C agonists, on food intake in the rat

被引:0
作者
Andrew J. Grottick
Kevin Whelan
Erin K. Sanabria
Dominic P. Behan
Michael Morgan
Carleton Sage
机构
[1] Arena Pharmaceuticals Inc,
来源
Psychopharmacology | 2015年 / 232卷
关键词
Synergy; BELVIQ®; Lorcaserin; Isobologram; Fen-phen;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1973 / 1982
页数:9
相关论文
共 191 条
[1]  
Balcioglu A(1998)Effects of fenfluramine and phentermine (fen-phen) on dopamine and serotonin release in rat striatum: in vivo microdialysis study in conscious animals Brain Res 813 67-72
[2]  
Wurtman RJ(1997)Valvular heart disease associated with fenfluramine-phentermine N Engl J Med 337 581-588
[3]  
Connolly HM(1997)Appetite suppression by commonly used drugs depends on 5-HT receptors but not on 5-HT availability Trends Pharmacol Sci 18 21-25
[4]  
Crary JL(2000)Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine Mol Pharmacol 57 75-81
[5]  
McGoon MD(2002)Inhibition of cocaine self-administration by fluoxetine or D-fenfluramine combined with phentermine Pharmacol Biochem Behav 71 197-204
[6]  
Hensrud DD(1997)Phentermine/fenfluramine decreases cocaine self-administration in rhesus monkeys Neuroreport 8 1347-1351
[7]  
Edwards BS(1992)Role of 5-HT receptors in the effect of d-fenfluramine on feeding patterns in the rat Eur J Pharmacol 212 287-289
[8]  
Edwards WD(2005)Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity Curr Drug Targets 6 201-213
[9]  
Schaff HV(1998)Interaction of phentermine plus fenfluramine: neurochemical and neurotoxic effects Neurotoxicology 19 177-184
[10]  
Curzon G(2000)Effects of phentermine and fenfluramine on alcohol consumption and alcohol withdrawal seizures in rats Alcohol 20 19-29