Mechanisms of transfer of bioactive molecules through the cell membrane by electroporation

被引：0
|
作者：
Mindaugas S. Venslauskas
Saulius Šatkauskas
机构：
[1] Vytautas Magnus University,Biophysical Research Group, Department of Biology, Faculty of Natural Sciences
来源：
European Biophysics Journal | 2015年 / 44卷
关键词：
Electroporation modeling; Drug and gene electrotransfer; Electrotransfer mechanisms; Electrochemotherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A short review of biophysical mechanisms for electrotransfer of biaoctive molecules through the cell membrane by using electroporation is presented. The concept of transient hydrophilic aqueous pores and membrane electroporation mechanisms of single cells and cells in suspension models are analyzed. Alongside the theoretical approach, some peculiarities of drug and gene electrotransfer into cells and applications in clinical trials are discussed.
引用
收藏
页码：277 / 289
页数：12
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