Con: are we ready to translate Alzheimer’s disease-modifying therapies to people with down syndrome?

被引:0
作者
Elizabeth Head
Frederick A Schmitt
机构
[1] Sanders-Brown Center on Aging,Department of Pharmacology and Nutritional Sciences
[2] University of Kentucky,Department of Neurology
[3] Sanders-Brown Center on Aging,undefined
[4] University of Kentucky,undefined
来源
Alzheimer's Research & Therapy | / 6卷
关键词
Dementia; Mild Cognitive Impairment; Down Syndrome; Intellectual Disability; Clinical Trial Outcome;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Neuropsychiatric Symptoms of Alzheimer's Disease in Down Syndrome and Its Impact on Caregiver Distress
    Fonseca, Luciana Mascarenhas
    Mattar, Guilherme Prado
    Haddad, Glenda Guerra
    Burduli, Ekaterina
    McPherson, Sterling M.
    de Figueiredo Ferreira Guilhoto, Laura Maria
    Yassuda, Monica Sanches
    Busatto, Geraldo Filho
    Bottino, Cassio Machado de Campos
    Hoexter, Marcelo Queiroz
    Chaytor, Naomi Sage
    JOURNAL OF ALZHEIMERS DISEASE, 2021, 81 (01) : 137 - 154
  • [42] Disease-modifying trials in Alzheimer's disease: a European task force consensus
    Vellas, Bruno
    Andrieu, Sandrine
    Sampaio, Cristina
    Wilcock, Gordon
    LANCET NEUROLOGY, 2007, 6 (01) : 56 - 62
  • [43] Towards Disease-Modifying Treatment of Alzheimer's Disease: Drugs Targeting β-Amyloid
    Frisardi, V.
    Solfrizzi, V.
    Imbimbo, B. P.
    Capurso, C.
    D'Introno, A.
    Colacicco, A. M.
    Vendemiale, G.
    Seripa, D.
    Pilotto, A.
    Capurso, A.
    Panza, F.
    CURRENT ALZHEIMER RESEARCH, 2010, 7 (01) : 40 - 55
  • [44] Noradrenergic System in Down Syndrome and Alzheimer's Disease A Target for Therapy
    Phillips, Cristy
    Fahimi, Atoossa
    Das, Devsmita
    Mojabi, Fatemeh S.
    Ponnusamy, Ravikumar
    Salehi, Ahmad
    CURRENT ALZHEIMER RESEARCH, 2016, 13 (01) : 68 - 83
  • [45] Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome
    Hamlett, Eric D.
    Goetzl, Edward J.
    Ledreux, Aurelie
    Vasilevko, Vitaly
    Boger, Heather A.
    LaRosa, Angela
    Clark, David
    Carroll, Steven L.
    Carmona-Iragui, Maria
    Fortea, Juan
    Mufson, Elliott J.
    Sabbagh, Marwan
    Mohammed, Abdul H.
    Hartley, Dean
    Doran, Eric
    Lott, Ira T.
    Granholm, Ann-Charlotte
    ALZHEIMERS & DEMENTIA, 2017, 13 (05) : 541 - 549
  • [46] Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in the Era of Disease-Modifying Treatments
    Paraskevas, George P.
    Kapaki, Elisabeth
    BRAIN SCIENCES, 2021, 11 (10)
  • [47] Plasma β-amyloid and duration of Alzheimer's disease in adults with Down syndrome
    Prasher, V. P.
    Sajith, S. G.
    Mehta, P.
    Zigman, W. B.
    Schupf, N.
    INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2010, 25 (02) : 202 - 205
  • [48] Experiences of supporting people with Down syndrome and Alzheimer's disease in aged care and family environments
    Carling-Jenkins, Rachel
    Torr, Jennifer
    Iacono, Teresa
    Bigby, Christine
    JOURNAL OF INTELLECTUAL & DEVELOPMENTAL DISABILITY, 2012, 37 (01) : 54 - 60
  • [49] Expanded disease definitions in Alzheimer's disease and the new era of disease-modifying drugs
    Yim, Su Jin
    Yasar, Sevil
    Schoenborn, Nancy
    Lang, Eddy
    BMJ EVIDENCE-BASED MEDICINE, 2025,
  • [50] Structural Connectivity in Down Syndrome and Alzheimer's Disease
    Saini, Fedal
    Dell'Acqua, Flavio
    Strydom, Andre
    FRONTIERS IN NEUROSCIENCE, 2022, 16