Detection of two porcine circovirus type 2 genotypic groups in United States swine herds

被引：0
作者：
A. K. Cheung
K. M. Lager
O. I. Kohutyuk
A. L. Vincent
S. C. Henry
R. B. Baker
R. R. Rowland
A. G. Dunham
机构：
[1] USDA-Agricultural Research Service,Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center
[2] Iowa State University,Department of Computer Science
[3] Abilene Animal Hospital PA,School of Veterinary Medicine
[4] North Carolina State University,Diagnostic Medicine and Pathobiology
[5] Kansas State University,undefined
[6] Ryan Veterinary Service,undefined
来源：
Archives of Virology | 2007年 / 152卷
关键词：
Capsid Gene; Porcine Circovirus Type; Postweaning Multisystemic Wasting Syndrome; Swine Herd; PCV2 Isolate;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In late 2005, sporadic cases of an acute onset disease of high mortality were observed in 10- to 16-week-old growing pigs among several swine herds of the United States. Tissues from the affected pigs in Kansas, Iowa, and North Carolina were examined, and porcine circovirus type 2 (PCV2) was detected consistently among these tissues. Phylogenetically, PCV2 can be divided into two major genotypic groups, PCV2-group 1 and PCV2-group 2. Whereas PCV2-group 1 isolates were detected in all the diseased animals, only two of the diseased animals harbored PCV2-group 2 isolates. This observation is important because PCV2-group 1 isolates had never been reported in the United States before (GenBank as of May 16, 2006), and they are closely related to the PCV2-group 1 isolates that have been described in Europe and Asia, previously. Our analysis revealed that each genotypic group contains a distinct stretch of nucleotide or amino acid sequence that may serve as a signature motif for PCV2-group 1 or PCV2-group 2 isolates.
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页码：1035 / 1044
页数：9
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