Activation of TGF-β/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts

被引:0
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作者
Naohiro Kon
Tsuyoshi Hirota
Takeshi Kawamoto
Yukio Kato
Tadashi Tsubota
Yoshitaka Fukada
机构
[1] Graduate School of Science,Department of Biophysics and Biochemistry
[2] The University of Tokyo,Department of Dental and Medical Biochemistry
[3] Hiroshima University Graduate School of Biomedical Sciences,undefined
来源
Nature Cell Biology | 2008年 / 10卷
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摘要
The circadian clock is synchronized with the environment. In mammals, besides light input mediated by Per genes, little is known about resetting mechanisms. TGF-β and activin reset the clock by acting on the circadian gene Dec1.
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页码:1463 / 1469
页数:6
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