A new dark energy model called “ghost dark energy” was recently suggested to explain the observed accelerating expansion of the universe. This model originates from the Veneziano ghost of QCD. The dark energy density is proportional to Hubble parameter, ρΛ = αH, where α is a constant of order ΛQCD3\documentclass[12pt]{minimal}
\usepackage{amsmath}
\usepackage{wasysym}
\usepackage{amsfonts}
\usepackage{amssymb}
\usepackage{amsbsy}
\usepackage{mathrsfs}
\usepackage{upgreek}
\setlength{\oddsidemargin}{-69pt}
\begin{document}${\Lambda }^{3}_{QCD}$\end{document} and ΛQCD ∼ 100MeV is QCD mass scale. In this paper, we investigate about the stability of generalized QCD ghost dark energy model against perturbations in the anisotropic background. At first, the ghost dark energy model of the universe with spatial BI model with/without the interaction between dark matter and dark energy is discussed. In particular, the equation of state and the deceleration parameters and a differential equation governing the evolution of this dark energy model are obtained. Then, we use the squared sound speed vs2\documentclass[12pt]{minimal}
\usepackage{amsmath}
\usepackage{wasysym}
\usepackage{amsfonts}
\usepackage{amssymb}
\usepackage{amsbsy}
\usepackage{mathrsfs}
\usepackage{upgreek}
\setlength{\oddsidemargin}{-69pt}
\begin{document}${v_{s}^{2}}$\end{document} the sign of which determines the stability of the model. We explore the stability of this model in the presence/absence of interaction between dark energy and dark matter in both flat and non-isotropic geometry. In conclusion, we find evidence that the ghost dark energy might can not lead to a stable universe favored by observations at the present time in BI universe.
