Mechanism of the blood pressure-lowering effect of sodium-glucose cotransporter 2 inhibitors in obese patients with type 2 diabetes

被引:0
作者
Shin Kawasoe
Yukiko Maruguchi
Shoko Kajiya
Hitoshi Uenomachi
Masaaki Miyata
Mariko Kawasoe
Takuro Kubozono
Mitsuru Ohishi
机构
[1] Kagoshima University,Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences
[2] Uenomachi-Kajiya Clinic,undefined
来源
BMC Pharmacology and Toxicology | / 18卷
关键词
Blood pressure; Natriuresis; Osmotic diuresis; SGLT2 inhibitor; Type 2 diabetes;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 230 条
[1]  
Ferrannini E(2012)Diabetes and hypertension: the bad companions Lancet 380 601-610
[2]  
Cushman WC(2011)Hypertension in people with type 2 diabetes: Update on pharmacologic management Can Fam Physician 57 997-1002
[3]  
Campbell NR(2008)Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes Int J Clin Pract 62 1279-1284
[4]  
Gilbert RE(2014)Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis J Am Soc Hypertens 8 262-275
[5]  
Leiter LA(2015)Safety, tolerability and effects on cardiometabolic risk factors of empagliflozin monotherapy in drug-naïve patients with type 2 diabetes: a double-blind extension of a Phase III randomized controlled trial Cardiovasc Diabetol 23 154-372
[6]  
Larochelle P(2015)Dapagliflozin improves glycemic control and reduces body weight as add-on therapy to metformin plus sulfonylurea: a 24-week randomized, double-blind clinical trial Diabetes Care 38 365-1932
[7]  
Tobe S(2014)Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined Phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative study Cardiovasc Diabetol 13 65-2128
[8]  
Chockalingam A(2015)Dapagliflozin lowers plasma glucose concentration and improves beta-cell function J Clin Endocrinol Metab 100 1927-334
[9]  
Ward R(2015)Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes N Engl J Med 373 2117-339
[10]  
Morris D(2016)Empagliflozin and progression of kidney disease in type 2 diabetes N Engl J Med 375 323-428