Roles of Sphingosine-1-Phosphate in Reproduction

被引：1
|
作者：
Lei Guo
Xianghong Ou
Hong Li
Zhiming Han
机构：
[1] Southern Medical University,Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Nanfang Hospital
[2] Chinese Academy of Sciences,State Key Laboratory of Reproductive Biology, Institute of Zoology
来源：
Reproductive Sciences | 2014年 / 21卷
关键词：
sphingosine-1-phosphate; ovary; germ cell; oocyte; preimplantation embryo;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Sphingosine-1-phosphate (S1P) plays crucial roles in the regulation of cell growth, proliferation, differentiation, cell survival, migration, and angiogenesis. In the reproductive system, S1P protects mammalian germ cells from irradiation or chemotherapy-induced cell death in vivo and in vitro. Moreover, S1P could improve the survival rate of thawed ovary and transplanted ovary. Furthermore, S1P could improve the developmental potential of oocyte and preimplantation embryo. In conclusion, S1P plays important roles in reproduction.
引用
收藏
页码：550 / 554
页数：4
相关论文
共 50 条
  • [1] Broad and diverse roles of sphingosine-1-phosphate/sphingosine-1-phosphate receptors in the prostate
    Liu, Daoquan
    Liu, Jianmin
    Li, Yan
    Du, Lu
    Cao, Qingqiong
    Yang, Liang
    Zhou, Yongying
    Chen, Ping
    Guo, Yuming
    Zeng, Guang
    Disanto, Michael E.
    Hu, Weidong
    Zhang, Xinhua
    ISCIENCE, 2024, 27 (12)
  • [2] The roles of sphingosine-1-phosphate in asthma
    Jolly, PS
    Rosenfeldt, HM
    Milstien, S
    Spiegel, S
    MOLECULAR IMMUNOLOGY, 2002, 38 (16-18) : 1239 - 1245
  • [3] Autocrine and paracrine roles of sphingosine-1-phosphate
    Alvarez, Sergio E.
    Milstien, Sheldon
    Spiegel, Sarah
    TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2007, 18 (08): : 300 - 307
  • [4] Roles of sphingosine-1-phosphate signaling in cancer
    Wang, Peng
    Yuan, Yonghui
    Lin, Wenda
    Zhong, Hongshan
    Xu, Ke
    Qi, Xun
    CANCER CELL INTERNATIONAL, 2019, 19 (01)
  • [5] Roles of sphingosine-1-phosphate signaling in cancer
    Peng Wang
    Yonghui Yuan
    Wenda Lin
    Hongshan Zhong
    Ke Xu
    Xun Qi
    Cancer Cell International, 19
  • [6] Inhibitors of sphingosine-1-phosphate metabolism (sphingosine kinases and sphingosine-1-phosphate lyase)
    Sanllehi, Pol
    Abad, Jose-Luis
    Casas, Josefina
    Delgado, Antonio
    CHEMISTRY AND PHYSICS OF LIPIDS, 2016, 197 : 69 - 81
  • [7] Roles of sphingosine-1-phosphate for eosinophil localization and function in mice
    Sugita, K.
    Kabashima, K.
    Sakabe, J.
    Yoshiki, R.
    Tokura, Y.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 : S13 - S13
  • [8] Roles of sphingosine-1-phosphate in cell growth, differentiation, and death
    Spiegel, S
    Cuvillier, O
    Edsall, L
    Kohama, T
    Menzeleev, R
    Olivera, A
    Thomas, D
    Tu, Z
    Van Brocklyn, J
    Wang, F
    BIOCHEMISTRY-MOSCOW, 1998, 63 (01) : 69 - 73
  • [9] Sphingosine kinases, sphingosine-1-phosphate and sphingolipidomics
    Maceyka, M
    Milstien, S
    Spiegel, S
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2005, 77 (1-4) : 15 - 22
  • [10] Sphingosine kinase, sphingosine-1-phosphate, and apoptosis
    Maceyka, M
    Payne, SG
    Milstien, S
    Spiegel, S
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2002, 1585 (2-3): : 193 - 201
12345