Endogenous endophthalmitis complicating klebsiella pneumoniae liver abscess in Europe: Case report

被引:29
作者
Karama E.M. [1 ]
Willermain F. [1 ]
Janssens X. [1 ]
Claus M. [2 ]
Van Den Wijngaert S. [3 ]
Wang J.-T. [4 ]
Verougstraete C. [1 ]
Caspers L. [1 ]
机构
[1] Department of Ophthalmology, CHU St-Pierre and Brugmann, Université Libre de Bruxelles, 1000 Bruxelles
[2] Intensive Care Unit, CHU St-Pierre, Université Libre de Bruxelles, 1000 Bruxelles
[3] Department of Microbiology, CHU St-Pierre, Université Libre de Bruxelles, 1000 Bruxelles
[4] Department of Microbiology, National Taiwan University College of Medicine, Taipei
关键词
Endophthalmitis; Virulence factor;
D O I
10.1007/s10792-007-9111-4
中图分类号
学科分类号
摘要
Purpose: To report the first European case of endogenous endophthalmitis secondary to a liver abscess due to Klebsiella pneumoniae expressing MagA gene. Methods: A 33-year-old diabetic patient was admitted for fever and right upper quadrant abdominal pain. Abdominal computed tomography and laboratory studies were performed. On day 4 after admission, patient complained of a painful and red right eye with decreased vision. A complete ophthalmological examination, including visual acuity assessment, slit lamp examination and fundus ophthalmoscopy was started. Results: Klebsiella pneumoniae liver abscess was diagnosed and antibiotherapy initiated. Polymerase chain reaction revealed that the isolated Klebsiella pneumoniae was serotype K1 and positive for Mag A. Ophthalmological examination disclosed cells in the anterior chamber and an important vitritis. Fundus was barely visible. A diagnosis of Klebsiella pneumoniae endogenous endophthalmitis complicating liver abscess was made. Intravitreal injection of antibiotics resulted in a preservation of visual acuity. Conclusion: This report suggests that rather than being confined to Taiwan, endogenous endophthalmitis secondary to a liver abscess due to Klebsiella pneumoniae expressing MagA gene, is becoming a global problem. © Springer Science+Business Media B.V. 2008.
引用
收藏
页码:111 / 113
页数:2
相关论文
共 10 条
  • [1] Fung C.-P., Chang F.-Y., Lee S.-C., Hu B.-S., Kuo B.I.-T., Liu C.-Y., Ho M., Siu L.K., A global emerging disease of Klebsiella pneumoniae liver abscess: Is serotype K1 an important factor for complicated endophthalmitis?, Gut, 50, 3, pp. 420-424, (2002)
  • [2] Lee C.-C., Chen C.-Y., Chen F.-H., Zimmerman R.A., Hsiao H.-S., Septic metastatic endophthalmitis from Klebsiella pneumoniae liver abscess: CT and MR imaging characteristics - Report of three cases, Radiology, 207, 2, pp. 411-416, (1998)
  • [3] Chen Y.J., Kuo H.K., Wu P.C., Kuo M.L., Tsai H.H., Liu C.C., Chen C.H., A 10-year comparison of endogenous endophthalmitis outcomes: An East Asian experience with K. Pneumoniae infection, Retina, 24, pp. 383-390, (2004)
  • [4] Cahill M., Chang B., Murray A., Bilateral endogenous bacterial endophthalmitis associated with pyogenic hepatic abscess, Br J Ophthalmol, 84, (2000)
  • [5] Harris E.W., D'Amico D.J., Bhisitkul R., Priebe G.P., Petersen R., Bacterial subretinal abscess: A case report and review of the literature, American Journal of Ophthalmology, 129, 6, pp. 778-785, (2000)
  • [6] Saccente M., Klebsiella pneumoniae liver abscess, endophthalmitis, and meningitis in a man with newly recognized diabetes mellitus, Clinical Infectious Diseases, 29, 6, pp. 1570-1571, (1999)
  • [7] Cobo M.F., Aliaga M.L., Diaz M.F., Liver abscess caused by klebsiella pneumoniae in diabetic patients, Rev Clin Esp, 199, pp. 517-519, (1999)
  • [8] Schiedler V., Scott I.U., Flynn Jr. H.W., Davis J.L., Benz M.S., Miller D., Culture-proven endogenous endophthalmitis: Clinical features and visual acuity outcomes, American Journal of Ophthalmology, 137, 4, pp. 725-731, (2004)
  • [9] Wang J.H., Liu Y.C., Lee S.S.J., Yen M.Y., Chen Y.S., Wang J.H., Wann S.R., Lin H.H., Primary liver abscess due to K. Pneumoniae in Taiwan, Clin Infec Dis, 26, pp. 1434-1438, (1998)
  • [10] Fang C.T., Chuang Y.P., Shun C.T., Chang S.C., Wang J.T., A novel virulence gene in K. Pneumoniae strains causing primary liver abscess and septic metastatic complications, J Exp Med, 199, pp. 697-705, (2004)