Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression

被引：0
|
作者：
Qing Ji
Xuan Liu
Zhifen Han
Lihong Zhou
Hua Sui
Linlin Yan
Haili Jiang
Jianlin Ren
Jianfeng Cai
Qi Li
机构：
[1] Shanghai University of Traditional Chinese Medicine,Department of Medical Oncology, Shuguang Hospital
[2] Shanghai University of Traditional Chinese Medicine,Research Center for Traditional Chinese Medicine and Systems Biology
[3] Department of Oncology,Shanghai Municipal Hospital of Traditional Chinese Medicine
[4] University of South Florida,Department of Chemistry
来源：
BMC Cancer | / 15卷
关键词：
Resveratrol; Colorectal cancer; Epithelial-to-mesenchymal transition; TGF-β1/Smads signaling pathway; Snail; E-cadherin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] VAV1 represses E-cadherin expression through the transactivation of Snail and Slug: a potential mechanism for aberrant epithelial to mesenchymal transition in human epithelial ovarian cancer
    Wakahashi, Senn
    Sudo, Tamotsu
    Oka, Noriko
    Ueno, Sayaka
    Yamaguchi, Satoshi
    Fujiwara, Kiyoshi
    Ohbayashi, Chiho
    Nishimura, Ryuichiro
    TRANSLATIONAL RESEARCH, 2013, 162 (03) : 181 - 190
  • [42] Prognostic significance of the epithelial-to-mesenchymal transition markers e-cadherin, vimentin and twist in bladder cancer
    Zhao, Jun
    Dong, Dahai
    Sun, Lingling
    Zhang, Guiming
    Sun, Lijiang
    INTERNATIONAL BRAZ J UROL, 2014, 40 (02): : 179 - 189
  • [43] Kruppel-like Factor 4 Inhibits Epithelial-to-Mesenchymal Transition through Regulation of E-cadherin Gene Expression
    Yori, Jennifer L.
    Johnson, Emhonta
    Zhou, Guangjin
    Jain, Mukesh K.
    Keri, Ruth A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (22) : 16854 - 16863
  • [44] MicroRNA-145 suppresses epithelial to mesenchymal transition in pancreatic cancer cells by inhibiting TGF-β signaling pathway
    Chen, Shaojun
    Xu, Junyi
    Su, Yao
    Hua, Li
    Feng, Chengjun
    Lin, Zhan
    Huang, Haixin
    Li, Yongqiang
    JOURNAL OF CANCER, 2020, 11 (09): : 2716 - 2723
  • [45] Quercetin restrains TGF-β1-induced epithelial-mesenchymal transition by inhibiting Twist1 and regulating E-cadherin expression
    Feng, Jihong
    Song, Dalong
    Jiang, SiYuan
    Yang, XiaoHui
    Ding, TingTing
    Zhang, Hong
    Luo, Junmin
    Liao, Jun
    Yin, Qian
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 498 (01) : 132 - 138
  • [46] Smoking Induces Epithelial-to-Mesenchymal Transition in Non-Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin
    Nagathihalli, Nagaraj S.
    Massion, Pierre P.
    Gonzalez, Adriana L.
    Lu, Pengcheng
    Datta, Pran K.
    MOLECULAR CANCER THERAPEUTICS, 2012, 11 (11) : 2362 - 2372
  • [47] Protein Kinase D1 Suppresses Epithelial-to-Mesenchymal Transition through Phosphorylation of Snail
    Du, Cheng
    Zhang, Chuanyou
    Hassan, Sazzad
    Biswas, Md. Helal Uddin
    Balaji, K. C.
    CANCER RESEARCH, 2010, 70 (20) : 7810 - 7819
  • [48] Notch signaling mediates TGF-β1-induced epithelial-mesenchymal transition through the induction of Snail
    Matsuno, Yosuke
    Coelho, Ana Lucia
    Jarai, Gabor
    Westvvick, John
    Hogaboam, Cory M.
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2012, 44 (05): : 776 - 789
  • [49] MEGF6 Promotes the Epithelial-to-Mesenchymal Transition via the TGFβ/SMAD Signaling Pathway in Colorectal Cancer Metastasis
    Hu, Hanqing
    Wang, Meng
    Wang, Hongwei
    Liu, Zheng
    Guan, Xu
    Yang, Runkun
    Huang, Rui
    Tang, Qingchao
    Zou, Chaoxia
    Wang, Guiyu
    Gao, Xu
    Wang, Xishan
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 46 (05) : 1895 - 1906
  • [50] E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma
    K Araki
    T Shimura
    H Suzuki
    S Tsutsumi
    W Wada
    T Yajima
    T Kobayahi
    N Kubo
    H Kuwano
    British Journal of Cancer, 2011, 105 : 1885 - 1893
12345