Role of dysregulated apoptosis in atopic dermatitis
被引:0
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作者:
A. Trautmann
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机构:Swiss Institute of Allergy and Asthma Research (SIAF),
A. Trautmann
M. Akdis
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机构:Swiss Institute of Allergy and Asthma Research (SIAF),
M. Akdis
K. Blaser
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机构:Swiss Institute of Allergy and Asthma Research (SIAF),
K. Blaser
C. A. Akdis
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机构:Swiss Institute of Allergy and Asthma Research (SIAF),
C. A. Akdis
机构:
[1] Swiss Institute of Allergy and Asthma Research (SIAF),
来源:
Apoptosis
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2000年
/
5卷
关键词:
T cells;
Keratinocytes;
eosinophils;
eczematous dermatitis;
eczema;
D O I:
暂无
中图分类号:
学科分类号:
摘要:
Atopic dermatitis is a chronic inflammatory skin disease with a complex immune dysregulation and interplay of genetic, environmental and psychological factors. Activation and skin-selective homing of peripherial-blood T cells, and effector functions in the skin, represent sequential events in the pathogenesis. Dysregulated apoptosis in skin-homing T cells, eosinophils and keratino-cytes contributes to the elicitation and persistence of atopic derrmatitis.
机构:
Indiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
Sehra, Sarita
Tuana, Florencia M. Barbe
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机构:
Indiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
Tuana, Florencia M. Barbe
Holbreich, Mark
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机构:
Indiana Univ, Sch Med, Dept Dermatol, Indianapolis, IN 46202 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
Holbreich, Mark
Mousdicas, Nico
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机构:
Indiana Univ, Sch Med, Dept Dermatol, Indianapolis, IN 46202 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
Mousdicas, Nico
Tepper, Robert S.
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h-index: 0
机构:
Indiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
Tepper, Robert S.
Chang, Cheong-Hee
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机构:
Univ Michigan, Sch Med, Dept Microbiol & Immunol, Ann Arbor, MI 48109 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
Chang, Cheong-Hee
Travers, Jeffrey B.
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机构:
Indiana Univ, Sch Med, Dept Dermatol, Indianapolis, IN 46202 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA
Travers, Jeffrey B.
Kaplan, Mark H.
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机构:
Indiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USAIndiana Univ, Sch Med, Herman B Wells Crt Pediat Res, Dept Pediat, Indianapolis, IN 46202 USA