Risk of venous thromboembolism in patients with rheumatoid arthritis: a systematic review and meta-analysis

被引:0
作者
Patompong Ungprasert
Narat Srivali
Ittikorn Spanuchart
Charat Thongprayoon
Eric L. Knight
机构
[1] Department of Internal Medicine,Department of Internal Medicine
[2] Bassett Medical Center and Columbia University College of Physicians and Surgeons,Division of Nephrology and Hypertension, Department of Medicine
[3] University of Hawaii,undefined
[4] Mayo Clinic,undefined
来源
Clinical Rheumatology | 2014年 / 33卷
关键词
Deep venous thrombosis; Pulmonary embolism; Rheumatoid arthritis; Venous thromboembolism;
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学科分类号
摘要
We performed this meta-analysis to assess venous thromboembolism risk in patients with rheumatoid arthritis. A comprehensive search was performed in MEDLINE, EMBASE, and the Cochrane databases. Nine observational studies met our inclusion criteria and were included in the data analysis. The pooled risk ratios of deep venous thrombosis, pulmonary embolism, and venous thromboembolism in patients with rheumatoid arthritis (RA) compared with non-RA participants were 2.08 (95 % CI 1.75–2.47), 2.17 (95 % CI 2.05–2.31), and 1.96 (95 % CI 1.81–2.11), respectively. Subgroup analysis demonstrated a consistent increased risk in every study design (cohort, case–control, and cross-sectional). Our results indicate a significant increased risk of venous thromboembolism among patients with rheumatoid arthritis.
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页码:297 / 304
页数:7
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