Humanized anti-DEspR IgG4S228P antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis ratnu/nu model

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作者
Christopher M. Gromisch
Glaiza L. A. Tan
Khristine Amber Pasion
Ann-Marie Moran
Matthew S. Gromisch
Mark W. Grinstaff
Francis J. Carr
Victoria L. M. Herrera
Nelson Ruiz-Opazo
机构
[1] Boston University School of Medicine,Department of Pharmacology
[2] Boston University School of Medicine,Whitaker Cardiovascular Institute and Department of Medicine
[3] Abtelum Biomedical,Department of Chemistry
[4] Inc.,undefined
[5] now NControl Therapeutics,undefined
[6] Inc.,undefined
[7] Boston University,undefined
来源
BMC Cancer | / 21卷
关键词
Dual endothelin-1/signal peptide receptor; DEspR; Cancer stem cells; Pancreatic cancer; Peritoneal carcinomatosis; Nude rat xenograft tumor model; IgG4 antibody therapy;
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