Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

被引：0

作者：

Matan Sorek

Walaa Oweis

Malka Nissim-Rafinia

Moria Maman

Shahar Simon

Cynthia C. Hession

Xian Adiconis

Sean K. Simmons

Neville E. Sanjana

Xi Shi

Congyi Lu

Jen Q. Pan

Xiaohong Xu

Mahmoud A. Pouladi

Lisa M. Ellerby

Feng Zhang

Joshua Z. Levin

Eran Meshorer

机构：

[1] The Hebrew University of Jerusalem,Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus

[2] The Hebrew University of Jerusalem,The Edmond and Lily Center for Brain Sciences, Edmond J. Safra Campus

[3] Broad Institute of MIT and Harvard,Stanley Center for Psychiatric Research

[4] Broad Institute of MIT and Harvard,Klarman Cell Observatory

[5] Broad Institute of MIT and Harvard,McGovern Institute for Brain Research

[6] Massachusetts Institute of Technology,New York Genome Center and Department of Biology

[7] New York University,Department of Neurology and Stroke Center, The First Affiliated Hospital

[8] Jinan University,Translational Laboratory in Genetic Medicine (TLGM), Agency for Science

[9] Technology and Research (A*STAR),Department of Physiology

[10] National University of Singapore,British Columbia Children’s Hospital Research Institute, Department of Medical Genetics

[11] University of British Columbia,Department of Biological Engineering

[12] Buck Institute for Research on Aging,Department of Brain and Cognitive Sciences

[13] Massachusetts Institute of Technology,undefined

[14] Massachusetts Institute of Technology,undefined

来源：

Genome Biology | / 22卷

关键词：

Transcriptional heterogeneity; Single cell; scRNA-seq; Neurological diseases; Neurodegenerative diseases; Huntington’s disease; Pluripotent stem cells; Stem cell model; Smart-seq2;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

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