Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway

被引:0
作者
Junchul Shin
Aki Nunomiya
Yasuo Kitajima
Takashi Dan
Toshio Miyata
Ryoichi Nagatomi
机构
[1] Tohoku University School of Medicine,Department of Medicine & Science in Sport & Exercise
[2] Tohoku University Graduate School of Biomedical Engineering,Division of Biomedical Engineering for Health and Welfare
[3] Tohoku University School of Medicine,Division of Molecular Medicine and Therapy, United Centers for Advanced Research and Translational Medicine (ART)
[4] Tohoku University School of Medicine,Center for Sports Medicine and Science, United Centers for Advanced Research and Translational Medicine (ART)
来源
Skeletal Muscle | / 6卷
关键词
Hypoxia-inducible factor α; Prolyl hydroxylate domain protein 2; Type I muscle fiber; Calcineurin; NFATc1;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 212 条
[1]  
Schiaffino S(1996)Molecular diversity of myofibrillar proteins: gene regulation and functional significance Physiol Rev 76 371-423
[2]  
Reggiani C(2014)Overexpression of TRB3 in muscle alters muscle fiber type and improves exercise capacity in mice Am J Physiol Regul Integr Comp Physiol 306 R925-33
[3]  
An D(1990)Co-existence of myosin heavy chain I and IIa isoforms in human skeletal muscle fibres with endurance training Pflugers Arch 416 470-2
[4]  
Lessard SJ(2007)Skeletal muscle fiber type conversion during the repair of mouse soleus: potential implications for muscle healing after injury J Orthop Res 25 1534-40
[5]  
Toyoda T(2013)Distinct and additive effects of sodium bicarbonate and continuous mild heat stress on fiber type shift via calcineurin/NFAT pathway in human skeletal myoblasts Am J Physiol Cell Physiol 305 C323-33
[6]  
Lee MY(2007)Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals J Biol Chem 282 30014-21
[7]  
Koh HJ(2012)Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics? J Cereb Blood Flow Metab 32 1347-61
[8]  
Qi L(2006)Knockdown of hypoxia-inducible factor-1alpha by siRNA inhibits C2C12 myoblast differentiation J Cell Biochem 98 642-9
[9]  
Klitgaard H(2014)Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor gamma coactivator (PGC)-1alpha J Biol Chem 289 8810-7
[10]  
Bergman O(2014)Expression of HIF-1alpha and VEGF in skeletal muscle of plateau animals in response to hypoxic stress Physiol Res 63 801-5