Bone marrow cytokeratin 19 mRNA level is an independent predictor of relapse-free survival in operable breast cancer patients

被引:0
作者
Ragne K. Farmen
Oddmund Nordgård
Bjørnar Gilje
Fuad V. Shammas
Jan T. Kvaløy
Satu Oltedal
Reino Heikkilä
机构
[1] Stavanger University Hospital,Department of Hematology and Oncology
[2] University of Stavanger,Department of Mathematics and Natural Science
[3] Stavanger University Hospital,Division of Research and Human Resources
[4] Gena AS,undefined
来源
Breast Cancer Research and Treatment | 2008年 / 108卷
关键词
Breast cancer; Bone marrow; Micrometastases; Real-time RT-PCR; Cytokeratin 19; Recurrence;
D O I
暂无
中图分类号
学科分类号
摘要
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页码:251 / 258
页数:7
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[1]  
Heimann R(2000)Clinical progression of breast cancer malignant behavior: what to expect and when to expect it. J Clin Oncol 18 591-599
[2]  
Hellman S(2005)Persistence of bone marrow micrometastases in patients receiving adjuvant therapy for breast cancer: results at 4 years. Int J Cancer 114 94-100
[3]  
Slade MJ(1994)Tumour cell detection in the bone marrow of breast cancer patients at primary therapy: results of a 3-year median follow-up. Br J Cancer 69 566-571
[4]  
Singh A(1996)Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status. J Natl Cancer Inst 88 1652-1658
[5]  
Smith BM(1999)of primary-breast-cancer patients with micrometastases: a long-term follow-up study. Lancet 354 197-202
[6]  
Tripuraneni G(2000)Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. N Engl J Med 342 525-533
[7]  
Hall E(2001)Time independence of the prognostic impact of tumor cell detection in the bone marrow of primary breast cancer patients. Clin Cancer Res 7 4102-4108
[8]  
Peckitt C(2001)Epithelial cells in bone marrow of breast cancer patients at time of primary surgery: clinical outcome during long-term follow-up. J Clin Oncol 19 3669-3674
[9]  
Harbeck N(2003)Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer J Clin Oncol 21 3469-3478
[10]  
Untch M(2004)Clinical significance of immunocytochemical detection of tumor cells using digital microscopy in peripheral blood and bone marrow of breast cancer patients. Clin Cancer Res 10 1392-1400