CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer

被引：0
作者：
Juan Ramón Tejedor
Alfonso Peñarroya
Javier Gancedo-Verdejo
Pablo Santamarina-Ojeda
Raúl F. Pérez
Sara López-Tamargo
Ana Díez-Borge
Juan J. Alba-Linares
Nerea González-del-Rey
Rocío G. Urdinguio
Cristina Mangas
Annalisa Roberti
Virginia López
Teresa Morales-Ruiz
Rafael R. Ariza
Teresa Roldán-Arjona
Mónica Meijón
Luis Valledor
María Jesús Cañal
Daniel Fernández-Martínez
María Fernández-Hevia
Paula Jiménez-Fonseca
Luis J. García-Flórez
Agustín F. Fernández
Mario F. Fraga
机构：
[1] Spanish National Research Council (CSIC),Nanomaterials and Nanotechnology Research Center (CINN)
[2] Health Research Institute of the Principality of Asturias (ISPA),Institute of Oncology of Asturias (IUOPA)
[3] Spanish Biomedical Research Network in Rare Diseases (CIBERER),Department of Organisms and Systems Biology, Institute of Biotechnology of Asturias
[4] University of Oviedo,Institute for Research in Biomedicine
[5] Viralgen Vector Core,Department of Genetics
[6] University of Oviedo,Division of General Surgery, Department of Colorectal Surgery
[7] The Barcelona Institute of Science and Technology,Division of Oncology, Department of Medical Oncology
[8] Maimónides Biomedical Research Institute of Córdoba (IMIBIC),Department of Surgery and Medical Surgical Specialties
[9] University of Córdoba,undefined
[10] Central University Hospital of Asturias (HUCA),undefined
[11] Central University Hospital of Asturias (HUCA),undefined
[12] University of Oviedo,undefined
来源：
Clinical Epigenetics | / 15卷
关键词：
DNA methylation; Gene expression; Epigenetics; Tumour suppressor gene; CRISPR screen; Colorectal cancer;
D O I：
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