Breast cancer survival in African American women: Is alcohol consumption a prognostic indicator?

被引：43
作者：
Green McDonald P.A. [1 ,2 ]
Williams R. [3 ]
Dawkins F. [4 ]
Adams-Campbell L.L. [1 ]
机构：
[1] Division of Cancer Prevention, Control and Population Sciences, Howard University, Cancer Center, Washington, DC
[2] National Institutes of Health, Bethesda, MD 20892
[3] Howard University Hospital Tumor Registry, Washington, DC
[4] Department of Medicine, Howard University, College of Medicine, Washington, DC
来源：
Cancer Causes & Control | 2002年 / 13卷 / 6期
基金：
美国国家卫生研究院;
关键词：
African American women; Alcohol consumption; Breast cancer; Postmenopausal; Survival;
D O I：
10.1023/A:1016337102256
中图分类号：
学科分类号：
摘要：
Objective: Compromised breast cancer survival in African American women is well established. Factors associated with poorer survival in this group are not fully elucidated. This analysis examined the influence of alcohol consumption on breast cancer survival in African American women accrued to a hospital-based study. Methods: One hundred twenty-five postmenopausal women (mean age = 64.2 ± 12.2 years) diagnosed with invasive breast carcinoma between August 1989 and December 1994, and accrued to a hospital-based study of the disease, were followed for survival through December 1998. Cox proportional hazards regression models, adjusted for cigarette smoking, summary stage of disease, and treatment explored the association between alcohol use and breast cancer survival. Results: Premorbid alcohol consumption of at least one drink per week was associated with 2.7-fold increase in risk of death (95% CI 1.3-5.8). Conclusions: This study suggests compromised breast cancer survival among postmenopausal women who reported drinking at least one alcoholic beverage per week, a preliminary finding that warrants further investigation.
引用
收藏
页码：543 / 549
页数：6
相关论文
共 48 条
[1]  
Chevarley F., White E., Recent trends in breast cancer mortality among white and black US women, Am J Public Health, 87, pp. 775-781, (1997)
[2]  
Ries L.A.G., Kosary C.L., Hankey B.F., Miller B.A., Edward B.K., SEER Cancer Statistics Review, 1973-1996, (1999)
[3]  
Chen V.W., Correa P., Kurman R.J., Et al., Histological characteristics of breast carcinoma in blacks and whites, Cancer Epidemiol Biomarkers Prev, 3, pp. 127-135, (1994)
[4]  
Eley J.W., Hill H.A., Chen V.W., Et al., Racial differences in survival from breast cancer. Results of the National Cancer Institute Black/White Cancer Survival Study, JAMA, 272, pp. 947-954, (1994)
[5]  
Weiss S.E., Tartter P.I., Ahmed S., Et al., Ethnic differences in risk and prognostic factors for breast cancer, Cancer, 76, pp. 268-274, (1995)
[6]  
Yood M.U., Johnson C.C., Blount A., Et al., Race and differences in breast cancer survival in a managed care population, J Natl Cancer Inst, 91, pp. 1487-1491, (1999)
[7]  
Joslyn S.A., West M.M., Racial differences in breast carcinoma survival, Cancer, 88, pp. 114-123, (2000)
[8]  
Elledge R.M., Clark G.M., Chamness G.C., Osborne C.K., Tumor biologic factors and breast cancer prognosis among white, Hispanic, and black women in the United States, J Natl Cancer Inst, 86, pp. 705-712, (1994)
[9]  
Krieger N., Van den Eeden S.K., Zava D., Okamoto A., Race/ethnicity, social class, and prevalence of breast cancer prognostic biomarkers: A study of white, black, and Asian women in the San Francisco bay area, Ethn Dis, 7, pp. 137-149, (1997)
[10]  
Bassett M.T., Krieger N., Social class and black-white differences in breast cancer survival, Am J Public Health, 76, pp. 1400-1403, (1986)
12345