DNA Methyltransferases and Structural-Functional Specificity of Eukaryotic DNA Modification

被引:0
作者
Ya. I. Buryanov
T. V. Shevchuk
机构
[1] Russian Academy of Sciences,Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Pushchino Branch
来源
Biochemistry (Moscow) | 2005年 / 70卷
关键词
DNA; methylation; DNA methyltransferases; CpG; CpNpG; CpNpN sequences; structure; functions; eukaryotes;
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学科分类号
摘要
Properties of the main families of mammalian, plant, and fungal DNA methyltransferases are considered. Structural-functional specificity of eukaryotic genome sequences methylated by DNA methyltransferases is characterized. The total methylation of cytosine in DNA sequences is described, as well as its relation with RNA interference. Mechanisms of regulation of expression and modulation of DNA methyltransferase activity in the eukaryotic cell are discussed.
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页码:730 / 742
页数:12
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