Molecular Mobility and Fragility in Indomethacin: A Thermally Stimulated Depolarization Current Study

被引：0
作者：
Natália T. Correia
Joaquim J. Moura Ramos
Marc Descamps
George Collins
机构：
[1] Centro de Química-Física Molecular,Laboratoire de Dynamique et Structure des Matériaux Moléculaires
[2] Complexo I,undefined
[3] IST,undefined
[4] UFR Physique,undefined
[5] TherMold Partners,undefined
[6] L.P.,undefined
来源：
Pharmaceutical Research | 2001年 / 18卷
关键词：
glass transition relaxation; secondary relaxations; glassy state; amorphous state;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To show that thermally stimulated depolarization currents (TSDC), which is a dielectric experimental technique relatively unknown in the pharmaceutical scientists community, is a powerful technique to study molecular mobility in pharmaceutical solids, below their glass transition temperature (Tg). Indomethacin (Tg = 42°C) is used as a model compound.
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页码：1767 / 1774
页数：7
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