Reproducibility of gallbladder ejection fraction measured by fatty meal cholescintigraphy

被引：6

作者：

Al-Muqbel K.M. ^{[1
]}

Bani Hani M.N. ^{[2
]}

Elheis M.A. ^{[1
]}

Al-Omari M.H. ^{[1
]}

机构：

[1] Department of Radiology and Nuclear Medicine, School of Medicine, Jordan University of Science and Technology, Irbid 22110

[2] Department of General Surgery, School of Medicine, Jordan University of Science and Technology, Irbid

来源：

Nuclear Medicine and Molecular Imaging | 2010年 / 44卷 / 4期

关键词：

CCK; Cholescintigraphy; Fatty meal; Gallbladder ejection fraction; Reproducibility;

D O I：

10.1007/s13139-010-0046-8

中图分类号：

学科分类号：

摘要：

Purpose: There are conflicting data in the literature regarding the reproducibility of the gallbladder ejection fraction (GBEF) measured by fatty meal cholescintigraphy (CS). We aimed to test the reproducibility of GBEF measured by fatty meal CS. Methods: Thirty-five subjects (25 healthy volunteers and 10 patients with chronic abdominal pain) underwent fatty meal CS twice in order to measure GBEF1 and GBEF2. The healthy volunteers underwent a repeat scan within 1-13 months from the first scan. The patients underwent a repeat scan within 1-4 years from the first scan and were not found to have chronic acalculous cholecystitis (CAC). Our standard fatty meal was composed of a 60-g Snickers chocolate bar and 200 ml full-fat yogurt. Results: The mean ± SD values for GBEF1 and GBEF2 were 52±17% and 52±16%, respectively. There was a direct linear correlation between the values of GBEF1 and GBEF2 for the subjects, with a correlation coefficient of 0.509 (p=0.002). Subgroup data analysis of the volunteer group showed that there was significant linear correlation between volunteer values of GBEF1 and GBEF2, with a correlation coefficient of 0.473 (p=0.017). Subgroup data analysis of the non-CAC patient group showed no significant correlation between patient values of GBEF1 and GBEF2, likely due to limited sample size. Conclusions: This study showed that fatty meal CS is a reliable test in gallbladder motility evaluation and that GBEF measured by fatty meal CS is reproducible. © Korean Society of Nuclear Medicine 2010.

引用

页码：246 / 251

页数：5

共 22 条

[1]

Misra Jr. D.C., Blossom G.B., Fink-Bennett D., Glover J.L., Results of surgical therapy for biliary dyskinesia, Arch Surg, 126, pp. 957-960, (1991)

[2]

Sorenson M.K., Fancher S., Lang N.P., Eidt J.F., Broadwater J.R., Abnormal gallbladder nuclear ejection fraction predicts success of cholecystectomy in patients with biliary dyskinesia, Am J Surg, 166, pp. 672-674, (1993)

[3]

Mishkind M.T., Pruitt R.F., Bambini D.A., Hakenewerth A.M., Thomason M.H., Zuger J.H., Et al., Effectiveness of cholecystokininstimulated cholescintigraphy in the diagnosis and treatment of acalculous gallbladder disease, Am Surg, 63, pp. 769-774, (1997)

[4]

Al-Muqbel K., Bani Hani M., Daradkeh M., Rashdan A., Usefulness of fatty meal-stimulated cholescintigraphy in the diagnosis and treatment of chronic acalculous cholecystitis, Ann Nucl Med, 23, pp. 137-142, (2009)

[5]

Al-Muqbel K.M., Diagnostic value of gallbladder emptying variables in chronic acalculous cholecystitis as assessed by fatty meal cholescintigraphy, Nucl Med Commun, 30, pp. 669-674, (2009)

[6]

Krishnamurthy G.T., Brown P.H., Comparison of fatty meal and intravenous cholecystokinin infusion for gallbladder ejection fraction, J Nucl Med, 43, pp. 1603-1610, (2002)

[7]

Ziessman H.A., Jones D.A., Muenz L.R., Agarval A.K., Cholecystokinin cholescintigraphy: methodology and normal values using a lactosefree fatty-meal food supplement, J Nucl Med, 44, pp. 1263-1266, (2003)

[8]

Bartel T.B., Juweid M.E., Ponto J.A., Graham M.M., Corn oil emulsion: a simple cholecystagogue for diagnosis of chronic acalculous cholecystitis, J Nucl Med, 46, pp. 67-74, (2005)

[9]

Xynos E., Pechlivanides G., Zoras O.J., Chrysos E., Tzovaras G., Fountos A., Et al., Reproducibility of gallbladder emptying scintigraphic studies, J Nucl Med, 35, pp. 835-839, (1994)

[10]

Mackie C.R., Baxter J.N., Grime J.S., Hulks G., Cuschieri A., Gallbladder emptying in normal subjects-a data base for clinical cholescintigraphy, Gut, 28, pp. 137-141, (1987)

← 1 2 3 →