Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial [ISRCTN47583497]

被引：0

作者：

Des Breen

Andreas Karabinis

Manu Malbrain

Rex Morais

Sven Albrecht

Inge-Lise Jarnvig

Pauline Parkinson

Andrew JT Kirkham

机构：

[1] Royal Hallamshire Hospital,Consultant in Anaesthesia and Intensive Care

[2] Genimatas General Hospital,Director of Intensive Care Unit

[3] ZiekenhuisNetwerk Antwerpen,Director of Intensive Care Unit

[4] Intensive Care Unit,Consultant Anaesthetist

[5] Dubai Hospital,Deputy Director

[6] Universität Erlangen-Nürnberg,Clinical Scientist, Neurosciences Medicines Development Centre

[7] Klinik für Anästhesiologie,Clinical Development Director, Neurosciences Medicines Development Centre

[8] Senior Registrar,undefined

[9] Intensive Care Unit,undefined

[10] Righospitalet,undefined

[11] GlaxoSmithKline,undefined

[12] GlaxoSmithKline,undefined

来源：

Critical Care | / 9卷

关键词：

Morphine; Mechanical Ventilation; Midazolam; Mean Arterial Pressure; Remifentanil;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 108 条

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[2] Lemmens HJ(1993)Pharmacokinetics of remifentanil (G187084B) and its major metabolite (GR90291) in patients undergoing elective surgery Anesthesiology 79 893-903
[3] Fiset P(1995)Measured context-sensitive half-times of remifentanil and alfentanil Anesthesiology 83 968-975
[4] Hermann DJ(2004)Pharmacokinetics of remifentanil and its major metabolite, remifentanil acid, in ICU patients with renal impairment Br J Anaesth 92 493-503
[5] Muir KT(2004)Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment Crit Care 8 R21-R30
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[8] Westmorland CL(1999)The use of remifentanil in critically ill patients. Clinical findings and early experience Anaesthesist 48 625-629
[9] Hoke JF(2000)Safety and feasibility of continuous infusion of remifentanil in the neurosurgical intensive care unit Neurosurgery 46 596-601
[10] Sebel PS(2004)Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit: a randomised control trial [ISRCTN43755713] Crit Care 8 R1-R11