Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort

被引：0

作者：

Renée T. Fortner

Danja Sarink

Helena Schock

Theron Johnson

Anne Tjønneland

Anja Olsen

Kim Overvad

Aurélie Affret

Mathilde His

Marie-Christine Boutron-Ruault

Heiner Boeing

Antonia Trichopoulou

Androniki Naska

Philippos Orfanos

Domenico Palli

Sabina Sieri

Amalia Mattiello

Rosario Tumino

Fulvio Ricceri

H. Bas Bueno-de-Mesquita

Petra H. M. Peeters

Carla H. Van Gils

Elisabete Weiderpass

Eiliv Lund

J. Ramón Quirós

Antonio Agudo

Maria-José Sánchez

María-Dolores Chirlaque

Eva Ardanaz

Miren Dorronsoro

Tim Key

Kay-Tee Khaw

Sabina Rinaldi

Laure Dossus

Marc Gunter

Melissa A. Merritt

Elio Riboli

Rudolf Kaaks

机构：

[1] German Cancer Research Center (DKFZ),Division of Cancer Epidemiology

[2] Diet,Section for Epidemiology, Department of Public Health

[3] Genes and Environment,Université Paris

[4] Danish Cancer Society Research Center,Saclay

[5] Aarhus University,WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics

[6] Université Paris-Sud,Cancer Risk Factors and Life

[7] UVSQ,Style Epidemiology Unit

[8] CESP,Dipartimento di Medicina Clinica e Chirurgia

[9] INSERM,Cancer Registry and Histopathology Unit

[10] Gustave Roussy,Unit of Cancer Epidemiology, Department of Medical Sciences

[11] Department of Epidemiology,Department of Epidemiology and Biostatistics, School of Public Health

[12] German Institute of Human Nutrition Potsdam-Rehbruecke,Department of Social & Preventive Medicine, Faculty of Medicine

[13] Hellenic Health Foundation,Department of Epidemiology

[14] University of Athens Medical School,MRC

[15] Cancer Research and Prevention Institute – ISPO,PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health

[16] Epidemiology and Prevention Unit,Department of Community Medicine, Faculty of Health Sciences

[17] Department of Preventive & Predictive Medicine Fondazione IRCCS Istituto Nazionale dei Tumori,Department of Medical Epidemiology and Biostatistics

[18] Federico II University,Genetic Epidemiology Group

[19] “Civic - M.p.Arezzo” Hospital,Department of Health and Social Sciences

[20] Unit of Epidemiology,Nuffield Department of Population Health

[21] Regional Health Service ASL TO3,Cancer Epidemiology Unit

[22] University of Turin,undefined

[23] Department for Determinants of Chronic Diseases (DCD),undefined

[24] National Institute for Public Health and the Environment (RIVM),undefined

[25] Imperial College London,undefined

[26] University of Malaya,undefined

[27] Julius Center for Health Sciences and Primary Care,undefined

[28] University Medical Center Utrecht,undefined

[29] Imperial College,undefined

[30] University of Tromsø,undefined

[31] The Arctic University of Norway,undefined

[32] Department of Research,undefined

[33] Cancer Registry of Norway,undefined

[34] Institute of Population-Based Cancer Research,undefined

[35] Karolinska Institutet,undefined

[36] Folkhälsan Research Center,undefined

[37] Public Health Directorate,undefined

[38] Unit of Nutrition and Cancer. Cancer Epidemiology Research Program. Catalan Institute of Oncology-IDIBELL. L’Hospitalet de Llobregat,undefined

[39] Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria ibs. GRANADA. Hospitales Universitarios de Granada/Universidad de Granada,undefined

[40] CIBER de Epidemiología y Salud Pública (CIBERESP),undefined

[41] Department of Epidemiology,undefined

[42] Regional Health Council,undefined

[43] IMIB-Arrixaca,undefined

[44] Universidad de Murcia,undefined

[45] Navarra Public Health Institute,undefined

[46] IdiSNA,undefined

[47] Navarra Institute for Health Research,undefined

[48] Public Health Direction and Biodonostia Research Institute CIBERESP,undefined

[49] Basque Regional Health Department,undefined

[50] University of Oxford,undefined

来源：

BMC Medicine | / 15卷

关键词：

Breast cancer; Osteoprotegerin; RANK axis; Hormone receptor; Estrogen receptor; Progesterone receptor;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 435 条

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Simonet WS(1997)Osteoprotegerin: a novel secreted protein involved in the regulation of bone density Cell 89 309-19

[2]

Lacey DL(2003)Osteoclast differentiation and activation Nature 423 337-42

[3]

Dunstan CR(1999)Breast cancer cells interact with osteoblasts to support osteoclast formation Endocrinology 140 4451-8

[4]

Kelley M(2000)Interactions between cancer and bone marrow cells induce osteoclast differentiation factor expression and osteoclast-like cell formation in vitro Biochem Biophys Res Commun 267 632-7

[5]

Chang MS(2015)Osteoprotegerin in breast cancer: beyond bone remodeling Mol Cancer 14 117-73

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Lüthy R(2015)Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis BMC Cancer 15 935-77

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Nguyen HQ(2009)The TRAIL to targeted therapy of breast cancer Adv Cancer Res 103 43-44

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Wooden S(2012)Breast cancer proteome takes more than two to tango on TRAIL: beat them at their own game J Membr Biol 245 763-30

[9]

Bennett L(2015)Association of osteoprotegerin with impaired glucose regulation and microalbuminuria: the REACTION study BMC Endocr Disord 15 75-91

[10]

Boone T(2011)Serum osteoprotegerin is a predictor for incident cardiovascular disease and mortality in a general population: the Tromsø study J Thromb Haemost 9 638-35

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