Successful treatment of methotrexate intolerance in juvenile idiopathic arthritis using eye movement desensitization and reprocessing – treatment protocol and preliminary results

[1] Beukelman T(2011)2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features Arthritis Care Res (Hoboken) 63 465-482

[2] Patkar NM(2017)Intra-articular corticosteroids versus intra-articular corticosteroids plus methotrexate in oligoarticular juvenile idiopathic arthritis: a multicentre, prospective, randomised, open-label trial Lancet 389 909-916

[3] Saag KG(2004)Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis J Rheumatol 31 2501-2506

[4] Tolleson-Rinehart S(2007)Psychological side effects of MTX treatment in juvenile idiopathic arthritis: a pilot study Clin Exp Rheumatol 25 480-485

[5] Cron RQ(2016)Mutations in the MTHFR gene are not associated with methotrexate intolerance in patients with juvenile idiopathic arthritis Pediatr Rheumatol Online J 14 11-2013

[6] DeWitt EM(2011)High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: development and validation of a methotrexate intolerance severity score Arthritis Rheum 63 2007-154

[7] Ilowite NT(2016)Methotrexate intolerance in oral and subcutaneous administration in patients with juvenile idiopathic arthritis: a cross-sectional, observational study Clin Exp Rheumatol 34 148-114

[8] Kimura Y(2012)High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients Br J Clin Pharmacol 73 106-77

[9] Laxer RM(2014)The role of eye movement desensitization and reprocessing (EMDR) therapy in medicine: addressing the psychological and physical symptoms stemming from adverse life experiences Perm J 18 71-2217

[10] Lovell DJ(2016)Pediatric seizure-related posttraumatic stress and anxiety symptoms treated with EMDR: a case series Eur J Psychotraumatol 7 2207-330

[1] Beukelman T(2011)2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features Arthritis Care Res (Hoboken) 63 465-482

[2] Patkar NM(2017)Intra-articular corticosteroids versus intra-articular corticosteroids plus methotrexate in oligoarticular juvenile idiopathic arthritis: a multicentre, prospective, randomised, open-label trial Lancet 389 909-916

[3] Saag KG(2004)Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis J Rheumatol 31 2501-2506

[4] Tolleson-Rinehart S(2007)Psychological side effects of MTX treatment in juvenile idiopathic arthritis: a pilot study Clin Exp Rheumatol 25 480-485

[5] Cron RQ(2016)Mutations in the MTHFR gene are not associated with methotrexate intolerance in patients with juvenile idiopathic arthritis Pediatr Rheumatol Online J 14 11-2013

[6] DeWitt EM(2011)High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: development and validation of a methotrexate intolerance severity score Arthritis Rheum 63 2007-154

[7] Ilowite NT(2016)Methotrexate intolerance in oral and subcutaneous administration in patients with juvenile idiopathic arthritis: a cross-sectional, observational study Clin Exp Rheumatol 34 148-114

[8] Kimura Y(2012)High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients Br J Clin Pharmacol 73 106-77

[9] Laxer RM(2014)The role of eye movement desensitization and reprocessing (EMDR) therapy in medicine: addressing the psychological and physical symptoms stemming from adverse life experiences Perm J 18 71-2217

[10] Lovell DJ(2016)Pediatric seizure-related posttraumatic stress and anxiety symptoms treated with EMDR: a case series Eur J Psychotraumatol 7 2207-330