Safety, tolerability, pharmacokinetics, and pharmacodynamics of low dose lysergic acid diethylamide (LSD) in healthy older volunteers

被引:0
作者
Neiloufar Family
Emeline L. Maillet
Luke T. J. Williams
Erwin Krediet
Robin L. Carhart-Harris
Tim M. Williams
Charles D. Nichols
Daniel J. Goble
Shlomi Raz
机构
[1] Eleusis Benefit Corporation,Department of Pharmacology and Experimental Therapeutics
[2] Imperial College London,undefined
[3] Bristol University,undefined
[4] LSU Health Sciences Center,undefined
[5] San Diego State University,undefined
来源
Psychopharmacology | 2020年 / 237卷
关键词
Inflammation; Serotonin; CNS; Neurodegenerative disease; Psychedelics; Clinical trial; Alzheimer’s; Immune system; 5-HT;
D O I
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中图分类号
学科分类号
摘要
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页码:841 / 853
页数:12
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[1]  
Bershad Anya(2019)S125. Subjective and Behavioral Effects of Microdoses of LSD in Healthy Human Volunteers Biological Psychiatry 85 S345-274
[2]  
Schepers Scott(2011)Cognitive enhancers for the treatment of ADHD Pharmacol Biochem Behav 99 262-2168
[3]  
Bremmer Michael(2015)Etanercept in Alzheimer disease: a randomized, placebo-controlled, double-blind, phase 2 trial Neurology 84 2161-794
[4]  
de Wit Harriet(2015)LSD enhances suggestibility in healthy volunteers Psychopharmacology 232 785-627
[5]  
Bidwell LC(2016)Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study Lancet Psychiatry 3 619-1162
[6]  
Joseph McClernon F(2004)A focus on the synapse for neuroprotection in Alzheimer disease and other dementias Neurology 63 1155-84
[7]  
Kollins SH(1998)The standardized psychometric assessment of altered states of consciousness (ASCs) in humans Pharmacopsychiatry 31 80-73
[8]  
Butchart J(2015)Pharmacokinetics and Concentration-Effect Relationship of Oral LSD in Humans International Journal of Neuropsychopharmacology 19 pyv072-848
[9]  
Brook L(2015)Depressive symptoms and biomarkers of Alzheimer’s disease in cognitively normal older adults Journal of Alzheimer’s Disease : JAD 46 63-962
[10]  
Hopkins V(2010)Drug-induced Valvulopathy: An Update Toxicologic Pathology 38 837-543