Non-sucrose sweetener for pain relief in sick Newborns

被引:9
作者
Ahuja V.K. [1 ]
Daga S.R. [1 ,2 ]
Gosavi D.V. [1 ]
Date A.M. [1 ]
机构
[1] Cama and Albless Hospital, Mumbai
[2] 1/11, Staff Quarters, J.J. Hospital
关键词
Non-sucrose sweetener; Pain relief;
D O I
10.1007/BF02760473
中图分类号
学科分类号
摘要
A prospective controlled blind study was carried out in the Special Care Unit for Newborns to assess the effect of commercially available sweetener on pain relief in newborns. Response to intramuscular injection and the pain stimulus was studied in twenty-five sick newborns, 13 preterm and 12 term, in a blinded fashion. Pain score, duration of cry, heart rate and oxygen saturations were studied. Basal response, responses with sterile water or sweetener were recorded in each baby. Responses to sweetener versus no solution and sweetener versus sterile water were compared by applying paired t-test. The reduction in pain score with sweetener was significant when compared with no solution. The difference was not significant when compared with sterile water. Similarly, duration of cry and heart rate with sweetener were significantly less when compared to sterile water or to no solution. However, the difference in oxygen saturation was not significantly different. Sweetener has an analgesic effect in sick babies. This can minimise adverse effects associated with painful procedures.
引用
收藏
页码:487 / 489
页数:2
相关论文
共 12 条
[1]  
Danford D.A., Mishe S., Headley J., Nelson R.M., Effects of routine care procedures on transcutaneous oxygen in neonates: A quantitative approach, Arch Dis Child, 58, pp. 20-23, (1983)
[2]  
Speidel B.D., Adverse effects of routine procedure on preterm infants, Lancet, 22, pp. 864-866, (1978)
[3]  
Simbriner G., Coradello H., Foder M., Havelac L., Lubec G., Pollak A., Effects of tracheal suction on oxygenation, circulation and lung mechanics in newborn infants, Arch Dis Child, 56, pp. 326-330, (1981)
[4]  
Blass E.M., Hoffmeyer L.B., Sucrose as an analgesic for newborn infants, Pediatrics, 87, pp. 215-218, (1991)
[5]  
Haouari N., Wood C., Griffith G., Levene M., The analgesic effect of sucrose in full term infants, BMJ, 310, pp. 1498-1500, (1995)
[6]  
Rameghi L.A., Wood C.M., Griffith G.C., Levene M.I., Reduction of pain response in premature infants using intraoral sucrose, Arch Dis Child, 74, (1996)
[7]  
Rameghi L.A., Griffith G.C., Wood C.M., Levene M.I., Effect of non-sucrose sweet tasting solution on neonatal heel prick responses, Arch Dis Child, 74, (1996)
[8]  
Grunau R.V.E., Craig K.D., Pain expression in neonates : Facial action and cry, Pain, 28, pp. 395-410, (1987)
[9]  
Rushforth J.A., Levene M.I., Behavioral response to pain in healthy neonates, Arch Dis Child, 70, pp. 174-176, (1994)
[10]  
Grunau R.V.E., Johnston C.C., Kraig K.D., Neonatal facial and cry responses to invasive and non-invasive procedures, Pain, 42, pp. 295-305, (1990)