When ADHD and substance use disorders intersect: Relationship and treatment implications

被引:27
作者
Wilens T.E. [1 ]
Fusillo S. [1 ]
机构
[1] Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114
基金
美国国家卫生研究院;
关键词
Cocaine; Bupropion; Atomoxetine; Acad Child Adolesc Psychiatry; Lisdexamfetamine;
D O I
10.1007/s11920-007-0053-3
中图分类号
学科分类号
摘要
There has been increasing interest in the overlap between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUDs). In this report, we describe the developmental relationship between ADHD and SUDs. ADHD alone and in combination with co-occurring psychopathology is a risk factor for the development of SUDs in adulthood. Conversely, approximately one fifth of adults with SUDs have ADHD. Pharmacotherapeutic treatment of ADHD in children reduces the risk for later cigarette smoking and SUDs in adulthood. In contrast, medication treatment alone of adults with ADHD and current SUD is inadequate for both ADHD and SUD. Stimulant diversion continues to be of concern, particularly in older adolescents and young adults. Copyright © 2007 by Current Medicine Group LLC.
引用
收藏
页码:408 / 414
页数:6
相关论文
共 52 条
[1]  
Kessler R.C., Adler L., Barkley R., Et al., The prevalence and correlates of adult ADHD in the United States: Results from the National Comorbidity Survey Replication, Am J Psychiatry, 163, pp. 716-723, (2006)
[2]  
Biederman J., Faraone S., Mick E., Age dependent decline of ADHD symptoms revisited: Impact of remission definition and symptom subtype, Am J Psychiatry, 157, pp. 816-817, (2000)
[3]  
Kessler R.C., McGonagle K.A., Zhao S., Et al., Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States, Arch Gen Psychiatry, 51, pp. 8-19, (1994)
[4]  
Wilens T., Attention-deficit/hyperactivity disorder and the substance use disorders: The nature of the relationship, subtypes at risk and treatment issues, Psychiatr Clin North Am, 27, pp. 283-301, (2004)
[5]  
Schubiner H., Tzelepis A., Milberger S., Et al., Prevalence of attention-deficit/hyperactivity disorder and conduct disorder among substance abusers, J Clin Psychiatry, 61, pp. 244-251, (2000)
[6]  
Levin F.R., Evans S., Kleber H.D., Prevalence of adult attention-deficit/ hyperactivity disorder among cocaine abusers seeking treatment, Drug Alcohol Depend, 52, pp. 15-25, (1998)
[7]  
Faraone S.V., Wilens T.E., Petty C., Et al., Substance use among ADHD adults: Implications of late onset and subthreshold diagnoses, Am J Addict, 16, SUPPL. 1, pp. 24-34, (2007)
[8]  
Milberger S., Biederman J., Faraone S., Et al., ADHD is associated with early initiation of cigarette smoking in children and adolescents, J Am Acad Child Adolesc Psychiatry, 36, pp. 37-44, (1997)
[9]  
Wilens T.E., Biederman J., Mick E., Et al., Attention deficit hyperactivity disorder (ADHD) is associated with early onset substance use disorders, J Nerv Ment Dis, 185, pp. 475-482, (1997)
[10]  
Pomerleau O., Downey K., Stelson F., Pomerleau C., Cigarette smoking in adult patients diagnosed with attention deficit hyperactivity disorder, J Subst Abuse, 7, pp. 373-378, (1995)