Cold adaptation modulates Ca2+ signaling in brown preadipocytes

被引：0
作者：
A. S. Baumuratov
B. B. Abzhalelov
L. I. Kramarova
L. P. Dolgacheva
V. P. Zinchenko
G. E. Bronnikov
机构：
[1] Russian Academy of Sciences,Institute of Cell Biophysics
[2] Russian Academy of Sciences,Institute of Theoretical and Experimental Biophysics
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 138卷 / 7期
关键词：
brown preadipocytes; adrenoceptors; Ca; signaling; cold adaptation;
D O I：
10.1007/BF02694473
中图分类号：
学科分类号：
摘要：
One-week cold exposure of mice led to a 2-fold increase in the density of α1-adrenoceptors in brown adipose tissue. The density of α1-adrenoceptors returned to normal after adaptation to cold for 2 weeks. The reduced Ca2+ signaling in stem cells of brown fat activated via β-adrenoceptors and cAMP was transformed into the Ca2+-system induced by α1-adrenoceptors and similar to that in mature brown adipocytes.
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页码：50 / 53
页数：3
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