Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens

被引:0
|
作者
M. Nisell
M. Marcus
G. G. Nomikos
T. H. Svensson
机构
[1] Karolinska Institutet,Department of Physiology and Pharmacology, Division of Pharmacology
来源
Journal of Neural Transmission | 1997年 / 104卷
关键词
Sensitization; tolerance; voltammetry; smoking;
D O I
暂无
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学科分类号
摘要
Like several drugs of abuse, nicotine increases dopamine (DA) release in the nucleus accumbens (NAC). In the present study, the effects of acute and chronic nicotine on DA output in two subdivisions of the NAC, the core and the shell, which are largely associated with motor control and limbic functions, respectively, were examined by means of in vivo differential normal pulse voltammetry in anesthetized, pargyline-treated rats.
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页码:1 / 10
页数:9
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