I-SPY 2: a Neoadjuvant Adaptive Clinical Trial Designed to Improve Outcomes in High-Risk Breast Cancer

被引：0

作者：

Haiyun Wang

Douglas Yee

机构：

[1] University of Minnesota,Masonic Cancer Center

来源：

Current Breast Cancer Reports | 2019年 / 11卷

关键词：

I-SPY 2; Breast cancer; Neoadjuvant chemotherapy; Pathological complete response; Adaptive randomization;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：303 / 310

页数：7

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[21] Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657) [J].

Laura J. Esserman ;

Donald A. Berry ;

Maggie C. U. Cheang ;

Christina Yau ;

Charles M. Perou ;

Lisa Carey ;

Angela DeMichele ;

Joe W. Gray ;

Kathleen Conway-Dorsey ;

Marc E. Lenburg ;

Meredith B. Buxton ;

Sarah E. Davis ;

Laura J. van’t Veer ;

Clifford Hudis ;

Koei Chin ;

Denise Wolf ;

Helen Krontiras ;

Leslie Montgomery ;

Debu Tripathy ;

Constance Lehman ;

Minetta C. Liu ;

Olufunmilayo I. Olopade ;

Hope S. Rugo ;

John T. Carpenter ;

Chad Livasy ;

Lynn Dressler ;

David Chhieng ;

Baljit Singh ;

Carolyn Mies ;

Joseph Rabban ;

Yunni-Yi Chen ;

Dilip Giri ;

Alfred Au ;

Nola Hylton .

Breast Cancer Research and Treatment, 2012, 132 :1049-1062

[22] Pathologic complete response (pCR) rates for patients with HRD/HER2L high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial [J].

Huppert, L. A. ;

Wolf, D. ;

Yau, C. ;

Brown-Swigart, L. ;

Hirst, G. L. ;

Isaacs, C. ;

Pusztai, L. ;

Pohlmann, P. R. ;

Demichele, A. ;

Shatsky, R. ;

Yee, D. ;

Thomas, A. ;

Nanda, R. ;

Perlmutter, J. ;

Heditsian, D. ;

Hylton, N. ;

Symmans, F. ;

van't Veer, L. J. ;

Esserman, L. ;

Rugo, H. S. .

ANNALS OF ONCOLOGY, 2025, 36 (02) :172-184

[23] Neoadjuvant paclitaxel for operable breast cancer: Multicenter phase II trial with clinical outcomes [J].

Kimura, Morihiko ;

Sano, Muneaki ;

Fujimori, Minoru ;

Nakagomi, Hiroshi ;

Negishi, Takeshi ;

Yanagita, Yasuhiro ;

Sato, Nobuaki .

ANTICANCER RESEARCH, 2008, 28 (2B) :1239-1244

[24] Utilization of neoadjuvant chemotherapy in high-risk, node-negative early breast cancer [J].

Prakash, Ipshita ;

Ben Neely, N. ;

Thomas, Samantha M. ;

Sammons, Sarah ;

Blitzblau, Rachel C. ;

DiLalla, Gayle A. ;

Hyslop, Terry ;

Menendez, Carolyn S. ;

Plichta, Jennifer K. ;

Rosenberger, Laura H. ;

Fayanju, Oluwadamilola M. ;

Hwang, E. Shelley ;

Greenup, Rachel A. .

CANCER MEDICINE, 2022, 11 (04) :1099-1108

[25] Predictive Factors of Long-Term Survival after Neoadjuvant Radiotherapy and Chemotherapy in High-Risk Breast Cancer [J].

Haussmann, Jan ;

Budach, Wilfried ;

Nestle-Kraemling, Carolin ;

Wollandt, Sylvia ;

Tamaskovics, Balint ;

Corradini, Stefanie ;

Boelke, Edwin ;

Krug, David ;

Fehm, Tanja ;

Ruckhaeberle, Eugen ;

Audretsch, Werner ;

Jazmati, Danny ;

Matuschek, Christiane .

CANCERS, 2022, 14 (16)

[26] MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial [J].

Chien, A. Jo ;

Tripathy, Debasish ;

Albain, Kathy S. ;

Symmans, W. Fraser ;

Rugo, Hope S. ;

Melisko, Michelle E. ;

Wallace, Anne M. ;

Schwab, Richard ;

Helsten, Teresa ;

Forero-Torres, Andres ;

Stringer-Reasor, Erica ;

Ellis, Erin D. ;

Kaplan, Henry G. ;

Nanda, Rita ;

Jaskowiak, Nora ;

Murthy, Rashmi ;

Godellas, Constantine ;

Boughey, Judy C. ;

Elias, Anthony D. ;

Haley, Barbara B. ;

Kemmer, Kathleen ;

Isaacs, Claudine ;

Clark, Amy S. ;

Lang, Julie E. ;

Lu, Janice ;

Korde, Larissa ;

Edmiston, Kirsten K. ;

Northfelt, Donald W. ;

Viscusi, Rebecca K. ;

Yee, Douglas ;

Perlmutter, Jane ;

Hylton, Nola M. ;

van't Veer, Laura J. ;

DeMichele, Angela ;

Wilson, Amy ;

Peterson, Garry ;

Buxton, Meredith B. ;

Paoloni, Melissa ;

Clennell, Julia ;

Berry, Scott ;

Matthews, Jeffrey B. ;

Steeg, Katherine ;

Singhrao, Ruby ;

Hirst, Gillian L. ;

Sanil, Ashish ;

Yau, Christina ;

Asare, Smita M. ;

Berry, Donald A. ;

Esserman, Laura J. .

JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (10) :1059-+

[27] Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer [J].

Kyalwazi, Beverly ;

Yau, Christina ;

Campbell, Michael J. ;

Yoshimatsu, Toshio F. ;

Chien, A. Jo ;

Wallace, Anne M. ;

Forero-Torres, Andres ;

Pusztai, Lajos ;

Ellis, Erin D. ;

Albain, Kathy S. ;

Blaes, Anne H. ;

Haley, Barbara B. ;

Boughey, Judy C. ;

Elias, Anthony D. ;

Clark, Amy S. ;

Isaacs, Claudine J. ;

Nanda, Rita ;

Han, Hyo S. ;

Yung, Rachel L. ;

Tripathy, Debasish ;

Edmiston, Kristen K. ;

Viscusi, Rebecca K. ;

Northfelt, Donald W. ;

Khan, Qamar J. ;

Asare, Smita M. ;

Wilson, Amy ;

Hirst, Gillian L. ;

Lu, Ruixiao ;

Symmans, William Fraser ;

Yee, Douglas ;

DeMichele, Angela M. ;

van 't Veer, Laura J. ;

Esserman, Laura J. ;

Olopade, Olufunmilayo I. .

JAMA NETWORK OPEN, 2023, 6 (12) :E2349646

[28] Analysis of tumor nuclear features using artificial intelligence to predict response to neoadjuvant chemotherapy in high-risk breast cancer patients [J].

Dodington, David W. ;

Lagree, Andrew ;

Tabbarah, Sami ;

Mohebpour, Majid ;

Sadeghi-Naini, Ali ;

Tran, William T. ;

Lu, Fang-, I .

BREAST CANCER RESEARCH AND TREATMENT, 2021, 186 (02) :379-389

[29] Deformable image registration as a tool to improve survival prediction after neoadjuvant chemotherapy for breast cancer: Results from the ACRIN 6657/I-SPY-1 trial [J].

Jahani, Nariman ;

Cohen, Eric ;

Hsieh, Meng-Kang ;

Weinstein, Susan P. ;

Pantalone, Lauren ;

Davatzikos, Christos ;

Kontos, Despina .

MEDICAL IMAGING 2018: COMPUTER-AIDED DIAGNOSIS, 2018, 10575

[30] Factors influencing pathological complete response and tumor regression in neoadjuvant radiotherapy and chemotherapy for high-risk breast cancer [J].