Food Allergy

被引:3
作者
Iweala O.I. [1 ,2 ]
Choudhary S.K. [1 ]
Commins S.P. [1 ,2 ]
机构
[1] Department of Medicine and Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC
[2] Thurston Research Center, Division of Allergy, Immunology and Rheumatology, University of North Carolina, 3300 Thurston Building, CB 7280, Chapel Hill, 27599-7280, NC
基金
美国国家卫生研究院;
关键词
Adult food allergy; Food allergy; Food immunotherapy; Peanut allergy; Specific IgE;
D O I
10.1007/s11894-018-0624-y
中图分类号
学科分类号
摘要
Purpose of Review: The goal of this review is to present an updated summary of the natural history of major childhood and adult food allergies and report recent advances in potential treatments for food allergy. Recent Findings: The most common childhood food allergies are typically outgrown by adolescence or adulthood. However, peanut/tree nut allergies appear to more commonly persist into adulthood. Adults can develop new IgE-mediated food allergies; the most common is oral allergy syndrome. There are multiple different approaches being tried as possible treatments for food allergy. Summary: The prevalence of food allergy appears to be increasing but the varied approaches to treatment are being actively pursued such that an approved modality may not be too far in the future. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
引用
收藏
相关论文
共 56 条
[41]  
Kim E.H., Bird J.A., Kulis M., Laubach S., Pons L., Shreffler W., Steele P., Kamilaris J., Vickery B., Burks A.W., Sublingual immunotherapy for peanut allergy: clinical and immunologic evidence of desensitization, J Allergy Clin Immunol, 127, pp. 640-650, (2011)
[42]  
Narisety S.D., Frischmeyer-Guerrerio P.A., Keet C.A., Gorelik M., Schroeder J., Hamilton R.G., Wood R.A., A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy, J Allergy Clin Immunol, 135, pp. 1275-1281, (2015)
[43]  
Fleischer D.M., Burks A.W., Vickery B.P., Scurlock A.M., Wood R.A., Jones S.M., Sicherer S.H., Liu A.H., Stablein D., Henning A.K., Mayer L., Lindblad R., Plaut M., Sampson H.A., Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trial, J Allergy Clin Immunol, 131, pp. 119-126, (2013)
[44]  
Burks A.W., Wood R.A., Jones S.M., Sicherer S.H., Fleischer D.M., Scurlock A.M., Et al., Sublingual immunotherapy for peanut allergy: Long-term follow-up of a randomized multicenter trial, J Allergy Clin Immunol, 135, pp. 1240-1250, (2015)
[45]  
Enrique E., Pineda F., Malek T., Bartra J., Basagana M., Tella R., Castello J.V., Alonso R., de Mateo J.A., Cerda-Trias T., San Miguel-Moncin M.M., Monzon S., Garcia M., Palacios R., Cistero-Bahima A., Sublingual immunotherapy for hazelnut food allergy: a randomized, double-blind, placebo-controlled study with a standardized hazelnut extract, J Allergy Clin Immunol, 116, pp. 1073-1080, (2005)
[46]  
Enrique E., Malek T., Pineda F., Bartra J., Basagana M., Tella R., Et al., Sublingual immunotherapy for hazelnut food allergy: a follow-up study, Ann Allergy Asthma Immunol, 100, pp. 283-289, (2008)
[47]  
Keet C.A., Frischmeyer-Guerrerio P.A., Thyagarajan A., Schroeder J.T., Hamilton R.G., Boden S., Steele P., Driggers S., Burks A.W., Wood R.A., The safety and efficacy of sublingual and oral immunotherapy for milk allergy, J Allergy Clin Immunol, 129, pp. 448-454, (2012)
[48]  
de Boissieu D., Dupont C., Sublingual immunotherapy for cow’s milk protein allergy: a preliminary report, Allergy, 61, pp. 1238-1243, (2006)
[49]  
Mempel M., Rakoski J., Ring J., Ollert M., Severe anaphylaxis to kiwi fruit: immunologic changes related to successful sublingual allergen immunotherapy, J Allergy Clin Immunol, 111, pp. 1406-1411, (2003)
[50]  
Kerzl R., Simonowa A., Ring J., Life-threatening anaphylaxis to kiwi fruit: protective sublingual allergen immunotherapy effect persists even after discontinuation, J Allergy Clin Immunol, 119, pp. 507-512, (2007)