Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury

被引:0
作者
Hongyu Zhang
Fenzan Wu
Xiaoxia Kong
Jie Yang
Huijun Chen
Liancheng Deng
Yi Cheng
Libing Ye
Sipin Zhu
Xie Zhang
Zhouguang Wang
Hongxue Shi
Xiaobing Fu
Xiaokun Li
Huazi Xu
Li Lin
Jian Xiao
机构
[1] Molecular Pharmacology Research Center,Key Laboratory of Biotechnology and Pharmaceutical Engineering
[2] School of Pharmacy,Department of Pharmacy
[3] Wenzhou Medical University,Department of Orthopaedics
[4] Cixi People’s Hospital,undefined
[5] Institute of Hypoxia Research,undefined
[6] School of Basic Medical Sciences,undefined
[7] Wenzhou Medical University,undefined
[8] The Second Affiliated Hospital,undefined
[9] Wenzhou Medical University,undefined
[10] Medicine Research Center,undefined
[11] Ningbo Medical Treatment Center Lihuili Hospital,undefined
[12] Institute of Basic Medical Sciences,undefined
[13] Chinese PLA General Hospital,undefined
来源
Journal of Translational Medicine | / 12卷
关键词
Nerve growth factor; Endoplasmic reticulum stress; Spinal cord injury; Apoptosis; Akt/GSK-3β; ERK1/2;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 325 条
[1]  
Penas C(2007)Spinal cord injury induces endoplasmic reticulum stress with different cell-type dependent response J Neurochem 102 1242-1255
[2]  
Guzman MS(2006)Therapeutic interventions after spinal cord injury Nat Rev Neurosci 7 628-643
[3]  
Verdu E(1996)Induction and its spread of apoptosis in rat spinal cord after mechanical trauma Neurosci Lett 216 9-12
[4]  
Fores J(2008)Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities Nat Rev Drug Discov 7 1013-1030
[5]  
Navarro X(2012)Endoplasmic reticulum enrollment in Alzheimer's disease Mol Neurobiol 46 522-534
[6]  
Casas C(2012)A thrombospondin-dependent pathway for a protective ER stress response Cell 149 1257-1268
[7]  
Thuret S(2012)Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress J Biol Chem 287 19687-19698
[8]  
Moon LD(2012)Activation of the unfolded protein response enhances motor recovery after spinal cord injury Cell Death Dis 3 e272-1502
[9]  
Gage FH(2011)Attenuating the endoplasmic reticulum stress response improves functional recovery after spinal cord injury Glia 59 1489-92
[10]  
Katoh K(2011)Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemia-reperfusion injury Neurosci Lett 504 88-13820