Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

被引:0
作者
Jennifer A. Smith
Jeremy Raisky
Scott M. Ratliff
Jiaxuan Liu
Sharon L. R. Kardia
Stephen T. Turner
Thomas H. Mosley
Wei Zhao
机构
[1] University of Michigan,Department of Epidemiology, School of Public Health
[2] University of Michigan,Survey Research Center, Institute for Social Research
[3] Mayo Clinic,Division of Nephrology and Hypertension
[4] University of Mississippi Medical Center,Memory Impairment and Neurodegenerative Dementia (MIND) Center
来源
BMC Medical Genomics | / 12卷
关键词
Epigenetic age; Age acceleration; DNA methylation; Target organ damage; Hypertension; Estimated glomerular filtration rate; Urinary albumin-creatinine ratio; Left ventricular mass; Relative wall thickness; White matter hyperintensity; Ankle-brachial index;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 478 条
[1]  
Merai R(2016)CDC grand rounds: a public health approach to detect and control hypertension MMWR Morb Mortal Wkly Rep 65 1261-1264
[2]  
Siegel C(2015)Heart disease and stroke statistics--2015 update: a report from the American Heart Association Circulation 131 e29-322
[3]  
Rakotz M(2006)Target organ damage in hypertension: pathophysiology and implications for drug therapy Curr Pharm Des 12 1581-1592
[4]  
Basch P(2012)Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies Circ Cardiovasc Genet 5 100-112
[5]  
Wright J(2012)Genome-wide association and functional follow-up reveals new loci for kidney function PLoS Genet 8 e1002584-409
[6]  
Wong B(2015)Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI Circ Cardiovasc Genet 8 398-46
[7]  
DHSc P(2013)Genome-wide association study of cardiac structure and systolic function in African Americans: the candidate Gene Association resource (CARe) study Circ Cardiovasc Genet 6 37-2192
[8]  
Thorpe D(2007)Telomere dysfunction in hypertension J Hypertens 25 2185-587
[9]  
Mozaffarian EJ(2005)Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures J Gerontol A Biol Sci Med Sci 60 574-47
[10]  
Benjamin AS(2017)Leukocyte telomere length and cardiovascular disease in African Americans: the Jackson heart study Atherosclerosis 266 41-411