Synthesis and anti-inflammatory and antipyretic activity of 2-(1′-hydroxy-4′-isopropenyl-1′-methylcyclohexyl-2′-thio)-methylethanoate

被引:0
作者
L. E. Nikitina
I. V. Akulina
R. S. Garaev
N. P. Artemova
L. Yu. Dorofeeva
V. A. Startseva
E. V. Sirazieva
机构
[1] Kazan State Medical University,
来源
Pharmaceutical Chemistry Journal | 2012年 / 46卷
关键词
synthesis; 2-(1′-hydroxy-4′-isopropenyl-1′-methylcyclohexyl-2′-thio)methylethanoate; (+)-1,2-limonene oxide; (+)-limonene; acute toxicity; anti-inflammatory activity; antipyretic activity;
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学科分类号
摘要
2-(1′-Hydroxy-4′-isopropenyl-1′-methylcyclohexyl-2′-thio)methylethanoate was synthesized via the reaction of (+)-1,2-limonene oxide with methylmercaptoacetate. The acute toxicity and anti-inflammatory and antipyretic activities of the starting compounds and the synthesized terpene sulfide were investigated.
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页码:20 / 22
页数:2
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