Gestational trophoblastic neoplasia: an update

被引：0
作者：
Jacqueline M. Morgan
John R. Lurain
机构：
[1] Northwestern University Feinberg School of Medicine,John I. Brewer Trophoblastic Disease Center
来源：
Current Oncology Reports | 2008年 / 10卷
关键词：
Choriocarcinoma; Hydatidiform Mole; Gestational Trophoblastic Disease; Trophoblastic Tumor; Multiagent Chemotherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, and placental site trophoblastic tumors. The overall cure rate in treating these tumors currently exceeds 90%. Thorough evaluation and staging allow selection of appropriate therapy that maximizes chances for cure while minimizing toxicity. Nonmetastatic (stage I) and low-risk metastatic (stages II and III, World Health Organization [WHO] score < 7) GTN can be treated with single-agent chemotherapy, resulting in a survival rate approaching 100%. High-risk metastatic GTN (stage IV, WHO score ≥ 7) requires initial multiagent chemotherapy with or without adjuvant radiation and surgery to achieve a survival rate of 80% to 90%.
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页码：497 / 504
页数：7
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