Efficient expression of functional human coagulation factor IX in stably-transfected Drosophila melanogaster S2 cells; comparison with the mammalian CHO system

[1] Bandyopadhyay P(2006)Biochemical characterization of Drosophilaγ-glutamyl carboxylase and its role in fly development Insect Mol Biol 15 147-156

[2] Clark K(2013)Hepatocyte clearance and pharmacokinetics of recombinant factor IX glycosylation variants Biochem Biophys Res Commun 440 485-489

[3] Stevenson B(2007)Transformation of drosophila cell lines: an alternative approach to exogenous protein expression Methods Mol Cell Biol 338 317-340

[4] Rivier J(2014)Glycosylation: impact, control and improvement during therapeutic protein production ‎Crit Rev Biotec 34 281-299

[5] Olivera B(2015)Human cell lines for biopharmaceutical manufacturing: history, status, and future perspectives ‎Crit Rev Biotec 10 941-950

[6] Golic K(2009)A systematic study of the function of the human beta-globin introns on the expression of the human coagulation factor IX in cultured CHO cells J Gene Med 3 2633-2648

[7] Rong Y(2005)Post-translational modifications in proteins involved in blood coagulation J Thromb Haemost 9 3295-3301

[8] Blasko E(1990)Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans-immortalized hepatic cell-lines EMBO J 57 51-59

[9] Brooks AR(2008)Expression of the hepatitis B virus surface antigen in Drosophila S2 cells Cytotechnology 133 116-122

[10] Ho E(2008)Recombinant baculovirus-based multiple protein expression platform for drosophila S2 cell culture J Biotechnol 142 275-278

[1] Bandyopadhyay P(2006)Biochemical characterization of Drosophilaγ-glutamyl carboxylase and its role in fly development Insect Mol Biol 15 147-156

[2] Clark K(2013)Hepatocyte clearance and pharmacokinetics of recombinant factor IX glycosylation variants Biochem Biophys Res Commun 440 485-489

[3] Stevenson B(2007)Transformation of drosophila cell lines: an alternative approach to exogenous protein expression Methods Mol Cell Biol 338 317-340

[4] Rivier J(2014)Glycosylation: impact, control and improvement during therapeutic protein production ‎Crit Rev Biotec 34 281-299

[5] Olivera B(2015)Human cell lines for biopharmaceutical manufacturing: history, status, and future perspectives ‎Crit Rev Biotec 10 941-950

[6] Golic K(2009)A systematic study of the function of the human beta-globin introns on the expression of the human coagulation factor IX in cultured CHO cells J Gene Med 3 2633-2648

[7] Rong Y(2005)Post-translational modifications in proteins involved in blood coagulation J Thromb Haemost 9 3295-3301

[8] Blasko E(1990)Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans-immortalized hepatic cell-lines EMBO J 57 51-59

[9] Brooks AR(2008)Expression of the hepatitis B virus surface antigen in Drosophila S2 cells Cytotechnology 133 116-122

[10] Ho E(2008)Recombinant baculovirus-based multiple protein expression platform for drosophila S2 cell culture J Biotechnol 142 275-278