Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer

被引:0
作者
Kie Kyon Huang
Jiawen Huang
Jeanie Kar Leng Wu
Minghui Lee
Su Ting Tay
Vikrant Kumar
Kalpana Ramnarayanan
Nisha Padmanabhan
Chang Xu
Angie Lay Keng Tan
Charlene Chan
Dennis Kappei
Jonathan Göke
Patrick Tan
机构
[1] Programme in Cancer and Stem Cell Biology,Cancer Science Institute of Singapore
[2] Duke-NUS Medical School,Department of Biochemistry
[3] National University of Singapore,undefined
[4] Yong Loo Lin School of Medicine,undefined
[5] National University of Singapore,undefined
[6] Genome Institute of Singapore,undefined
[7] SingHealth/Duke-NUS Institute of Precision Medicine,undefined
[8] National Heart Centre Singapore,undefined
来源
Genome Biology | / 22卷
关键词
Gastric cancer; Alternative splicing; Alternative promoter; Iso-seq;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 297 条
[11]  
Lee JS(2019)Unveiling novel targets of paclitaxel resistance by single molecule long-read RNA sequencing in breast cancer Sci Rep 9 55-19
[12]  
Cho JY(2019)Evaluation and application of RNA-Seq by MinION DNA Res 26 1859-15781
[13]  
Cheong JH(2005)GMAP: a genomic mapping and alignment program for mRNA and EST sequences Bioinformatics. 21 8-219
[14]  
Liu J(2018)Characterization of drug-induced splicing complexity in prostate cancer cell line using long read technology Pac Symp Biocomput 23 15776-443
[15]  
McCleland M(2003)Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage Proc Natl Acad Sci U S A 100 213-527
[16]  
Stawiski EW(2013)Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples Nat Biotechnol 31 434-3368
[17]  
Gnad F(2020)The mutational constraint spectrum quantified from variation in 141,456 humans Nature. 581 525-E4830
[18]  
Mayba O(2016)Near-optimal probabilistic RNA-seq quantification Nat Biotechnol 34 3360-2319
[19]  
Haverty PM(2017)NetMHCpan-4.0: improved peptide-MHC class I interaction predictions integrating eluted ligand and peptide binding affinity data J Immunol 199 40-651
[20]  
Kahles A(2018)SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions Genome Biol 19 3328-145