Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer

被引:0
作者
Kie Kyon Huang
Jiawen Huang
Jeanie Kar Leng Wu
Minghui Lee
Su Ting Tay
Vikrant Kumar
Kalpana Ramnarayanan
Nisha Padmanabhan
Chang Xu
Angie Lay Keng Tan
Charlene Chan
Dennis Kappei
Jonathan Göke
Patrick Tan
机构
[1] Programme in Cancer and Stem Cell Biology,Cancer Science Institute of Singapore
[2] Duke-NUS Medical School,Department of Biochemistry
[3] National University of Singapore,undefined
[4] Yong Loo Lin School of Medicine,undefined
[5] National University of Singapore,undefined
[6] Genome Institute of Singapore,undefined
[7] SingHealth/Duke-NUS Institute of Precision Medicine,undefined
[8] National Heart Centre Singapore,undefined
来源
Genome Biology | / 22卷
关键词
Gastric cancer; Alternative splicing; Alternative promoter; Iso-seq;
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[1]  
Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
[2]  
Ferlay J(1965)The two histological Main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification Acta Pathol Microbiol Scand 64 31-49
[3]  
Soerjomataram I(2012)AMPKalpha modulation in cancer progression: multilayer integrative analysis of the whole transcriptome in Asian gastric cancer Cancer Res 72 2512-2521
[4]  
Siegel RL(2014)Comprehensive molecular characterization of gastric adenocarcinoma Nature. 513 202-209
[5]  
Torre LA(2014)Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer Nat Commun 5 3830-224
[6]  
Jemal A(2018)Comprehensive analysis of alternative splicing across tumors from 8,705 patients Cancer Cell 34 211-1477
[7]  
Lauren P(2019)A pan-cancer transcriptome analysis reveals pervasive regulation through alternative promoters Cell. 178 1465-9874
[8]  
Kim YH(2014)High-resolution transcriptome analysis with long-read RNA sequencing PLoS One 9 9869-1135
[9]  
Liang H(2014)Defining a personal, allele-specific, and single-molecule long-read transcriptome Proc Natl Acad Sci U S A 111 1126-65
[10]  
Liu X(2018)Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line Genome Res 28 6032-1875