Successful use of inhaled nitric oxide to decrease intracranial pressure in a patient with severe traumatic brain injury complicated by acute respiratory distress syndrome: a role for an anti-inflammatory mechanism?

被引：0
作者：
Thomas J Papadimos
Azedine Medhkour
Sooraj Yermal
机构：
[1] University of Toledo,Department of Anesthesiology, College of Medicine
[2] University of Michigan,Department of Anesthesiology, School of Medicine
[3] University of Toledo,Deparment of Surgery, Division of Neurosurgery, College of Medicine
来源：
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | / 17卷
关键词：
Nitric Oxide; Traumatic Brain Injury; Glucocorticoid Receptor; Acute Respiratory Distress Syndrome; Cerebral Perfusion Pressure;
D O I：
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中图分类号：
学科分类号：
摘要：
Use of inhaled nitric oxide in humans with traumatic brain injury and acute respiratory distress syndrome has twice previously been reported to be beneficial. Here we report a third case. We propose that INO may decrease the inflammatory response in patients with increased intracranial pressure caused by traumatic brain injury accompanied by acute respiratory distress syndrome thereby contributing to improved outcomes.
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  • [1] Thurman D(1999)Traumatic brain injury in the United States: a public health perspective J Head Trauma Rehabil 14 602-615
  • [2] Alverson C(2005)Hyperventilation in head injury: a review Chest 127 1812-1827
  • [3] Dunn K(2002)Inflammatory response in acute brain injury: a double-edged sword Curr Opin Crit Care 8 101-105
  • [4] Guerrero J(2003)Comparative analysis of mRNA levels in the frontal cortex and the hippocampus in the basal state and in response to experimental brain injury Neuropathol Appl Neurobiol 29 18-131
  • [5] Sniezek J(2005)Massive brain injury enhances lung damage in an isolated lung model of ventilator-induced injury Crit Care Med 33 1077-1083
  • [6] Stocchetti N(2005)Non-neurologic organ dysfunction in severe traumatic brain injury Crit Care Med 33 654-660
  • [7] Maas AIR(2006)Ventilator-associated pneumonia in severe traumatic brain injury Neurocrit Care 5 108-114
  • [8] Chieregato A(2003)The development of acute lung injury is associated with worse neurologic outcome in patients with severe traumatic brain injury J Trauma 55 106-111
  • [9] Plas AA van der(2004)Ultrastructural changes in pneumatocyte type II cells following traumatic brain injury in rats Eur J Cardiothorac Surg 25 523-529
  • [10] Moranti-Kossman MC(1994)Acute Lung Injury: the role of cytokines in the elicitation of neutrophils J Investig Med 42 640-651
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