Co-existence of a giant splenic hemangioma and multiple hepatic hemangiomas and the potential association with the use of oral contraceptives: A case report

被引：11

作者：

Chatzoulis G. ^{[1
]}

Kaltsas A. ^{[1
]}

Daliakopoulos S. ^{[1
]}

Sallam O. ^{[2
]}

Maria K. ^{[4
]}

Chatzoulis K. ^{[1
]}

Pachiadakis I. ^{[3
]}

机构：

[1] Department of Surgery, Military Hospital, 54636 Thessaloniki

[2] Department of Pathology, St Loukas Hospital, Thessaloniki

[3] Department of Gastroenterology, Military Hospital Thessaloniki, Thessaloniki

[4] Department of Linguistics, University of Cambridge, Cambridge

来源：

Journal of Medical Case Reports | / 2卷 / 1期

关键词：

Endometriosis; Hemangioma; Cavernous Hemangioma; Hepatic Hemangioma; Estrogen Administration;

D O I：

10.1186/1752-1947-2-147

中图分类号：

学科分类号：

摘要：

Introduction: Hepatic and splenic hemangiomas are common benign tumors that mainly affect female patients. Giant splenic hemangiomas are extremely rare, especially when correlated with multiple hepatic hemangiomas. Pathogenetic mechanisms between hemangiomas and oral contraceptives, as well as therapeutic approaches, are analyzed in this case report, in particular for the management of synchronous splenic and hepatic hemangiomas. Case presentation: We report here a 42-year-old woman with a giant splenic hemangioma, multiple hepatic hemangiomas and a history of oral estrogen intake for many years. At first it was difficult to determine the organ from which the giant hemangioma originated. Angiography proved extremely helpful in tracing its origin in the spleen. Hematomas in the giant hemangioma posed a significant threat of rupture and catastrophic hemorrhage. We left the small hepatic hemangiomas in place, and removed the spleen along with the giant splenic hemangioma. Conclusion: Diagnostic pitfalls in the determination of the origin of this giant hemangioma, attribution of its origin to the spleen angiographically, the unusual co-existence of the giant splenic hemangioma with multiple hepatic ones, and the potential threat of rupture of the giant hemangioma are some of the highlights of this case report. Estrogen administration represents a pathogenic factor that has been associated with hemangiomas in solid organs of the abdominal cavity. The therapeutic dilemma between resection and embolization of giant hemangiomas is another point of discussion in this case report. Splenectomy for the giant splenic hemangioma eliminates the risk of rupture and malignant degeneration, whereas observation for the small hepatic ones (<4 cm) was the preferable therapeutic strategy in our patient. © 2008 Chatzoulis et al; licensee BioMed Central Ltd.

引用

共 14 条

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