The Role of Biomarkers in the Diagnostics of acute Mesenteric Ischemia (vol 86, pg 47, 2015)

被引：0

作者：

Reichert, M. ^{[1
]}

Hecker, M. ^{[2
]}

Hoerbelt, R. ^{[1
]}

Lerner, S. ^{[1
]}

Holler, J. ^{[1
]}

Hecker, C. M. ^{[3
]}

Padberg, W. ^{[1
]}

Weigand, M. A. ^{[4
]}

Hecker, A. ^{[1
]}

机构：

[1] Univ Klin Giessen & Marburg GmbH, Klin Allgemein Viszeral Thorax Transplantat & Kin, Standort Giessen, D-35392 Giessen, Germany

[2] Univ Giessen, Univ Klin Giessen & Marburg GmbH, Med Klin 2, Standort Giessen,Lung Ctr, Giessen, Germany

[3] Max Planck Inst Mol Physiol, Abt Syst Zellbiol, D-44139 Dortmund, Germany

[4] Univ Klin Giessen & Marburg GmbH, Klin Anasthesie Intens Med & Schmerztherapie, Standort Giessen, D-35392 Giessen, Germany

来源：

CHIRURG | 2015年 / 86卷 / 01期

关键词：

Acute mesenteric ischemia; Biomarker; Lactate; Pathophysiology; Symptoms;

D O I：

10.1007/s00104-014-2906-8

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Acute mesenteric ischemia is a severe and challenging disease. Unspecific symptoms in the initial phase make a fast diagnosis difficult although it is of major importance to protect patients from irreversible ischemia, extended bowel resection, sepsis and death in the late phase. In contrast to troponin as an early biomarker for cardiac ischemia, a reliable biomarker for acute intestinal ischemia has not yet been identified in the current literature and clinical practice. This would allow the early identification of these critically ill patients in the initial reversible phase of acute intestinal ischemia. This review highlights the pathophysiology, epidemiology and clinical findings of acute mesenteric ischemia and gives an overview of biomarkers which have been investigated in mesenteric ischemia with a special focus on lactate, which is the only parameter routinely used in the diagnostic setting of acute mesenteric ischemia.

引用

页码：55 / 55

页数：1