The microbiota in inflammatory bowel disease

被引：0
作者：
Donal Sheehan
Carthage Moran
Fergus Shanahan
机构：
[1] University College Cork,Department of Medicine
[2] National University of Ireland,Alimentary Pharmabiotic Centre
[3] University College Cork,undefined
[4] National University of Ireland,undefined
来源：
Journal of Gastroenterology | 2015年 / 50卷
关键词：
Inflammatory bowel disease; Gut microbiota; Mycobiome; Virome; Faecal microbial transplantation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This review explores our current understanding of the complex interaction between environmental risk factors, genetic traits and the development of inflammatory bowel disease. The primacy of environmental risk factors is illustrated by the rapid increase in the incidence of the disease worldwide. We discuss how the gut microbiota is the proximate environmental risk factor for subsequent development of inflammatory bowel disease. The evolving fields of virome and mycobiome studies will further our understanding of the full potential of the gut microbiota in disease pathogenesis. Manipulating the gut microbiota is a promising therapeutic avenue.
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页码：495 / 507
页数：12
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