Reaction of 3-[(alkylsulfanyl)methyl]pentane-2,4-diones with nicotinic hydrazide

被引：0
作者：
Larisa A. Baeva
Radik M. Nugumanov
Rail R. Gataullin
Akhnef А. Fatykhov
机构：
[1] Ufa Federal Research Center of the Russian Academy of Sciences,Ufa Institute of Chemistry
来源：
Chemistry of Heterocyclic Compounds | 2020年 / 56卷
关键词：
1-acyl-1; -pyrazole; 3-[(alkylsulfanyl)methyl]pentane-2,4-dione; nicotinic hydrazide; 1-(pyridin-3-yl)carbonyl-1; -pyrazole; heterocyclization;
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摘要：
The reaction of 3-[(alkylsulfanyl)methyl]pentane-2,4-diones with nicotinic hydrazide in ethanol as solvent produces 4-[(alkylsulfanyl)- methyl]-substituted 1-(pyridin-3-yl)carbonyl-1H-pyrazoles, whereas 1-acyl-1H-pyrazoles are formed in acetic, propanoic, or pentanoic acid solution. The reaction in methanol in the presence of ZnCl2 is accompanied by elimination of nicotinic acid and the formation of (alkylsulfanyl)methyl-substituted 1H-pyrazoles.
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页码：548 / 554
页数：6
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