Single-molecule analysis of protein-free U2–U6 snRNAs

被引：0
作者：
Zhuojun Guo
Krishanthi S Karunatilaka
David Rueda
机构：
[1] Wayne State University,Department of Chemistry
来源：
Nature Structural & Molecular Biology | 2009年 / 16卷
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摘要：
The U2–U6 snRNA complex is argued to adopt different conformations during splicing. Using single-molecule FRET, the dynamics of an RNA representing U2–U6 are now probed and related to splicing steps through probing of mutations previously linked to this process.
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页码：1154 / 1159
页数：5
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