Immunohistochemical studies of the expression of matrix metalloproteinase-2 and metalloproteinase-9 in human prostate cancer

被引：0

作者：

Zeng Hanqing

Xiao Yajun

Lu Gongchen

Chen Yong

机构：

[1] Huazhong University of Science and Technology,Department of Urology, Union Hospital, Tongji Medical College

[2] Wuhan University,Department of Urology, Zhongnan Hospital

来源：

Current Medical Science | 2003年 / 23卷 / 4期

关键词：

prostate cancer; matrix metalloproteinase-2; matrix metalloproteinase-9; immunohistochemistry;

D O I：

10.1007/BF02829421

中图分类号：

学科分类号：

摘要：

To study the expression of matrix metalloproteinase-2 and-9 in human prostate cancer, matrix metalloproteinase-2 and-9 were immunohistochemically detected in tissues of prostate cancer and benign prostatic hyperplasia (BPH). Our results showed that matrix metalloproteinase-2 and-9 levels in prostate cancer were much higher than those in tissues of BPH, with the cancer invasion being positively correlated with the expression of the metalloproteinases. It is concluded that matrix metalloproteinase-2 and-9 are better molecular markers, which are of help in the diagnosis and prediction of prognosis of prostate cancer.

引用

页码：373 / 374

页数：1

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